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Article
Open AccessStrain-graded quantum dots with spectrally pure, stable and polarized emission
Structural deformation modifies the bandgap, exciton fine structure and phonon energy of semiconductors, providing an additional knob to control their optical properties. The impact can be exploited in colloid...
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Article
Open AccessAngiotensin Receptor Blockers and the Risk of Suspected Drug-Induced Liver Injury: A Retrospective Cohort Study Using Electronic Health Record-Based Common Data Model in South Korea
Angiotensin receptor blockers are widely used antihypertensive drugs in South Korea. In 2021, the Korea Ministry of Food and Drug Safety acknowledged the need for national compensation for a drug-induced liver...
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Article
Investigating chiral morphogenesis of gold using generative cellular automata
Homochirality is an important feature in biological systems and occurs even in inorganic nanoparticles. However, the mechanism of chirality formation and the key steps during growth are not fully understood. H...
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Article
Bridging terahertz metal slot antenna with parameterized electrical conductivity: insights from finite element method and microscopic theory
Metal slot antennas exhibit high transmission characteristics at resonant frequencies when electromagnetic waves with polarization in the width direction of the rectangular hole structure enter, having wavelen...
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Article
Micro-scale gas tungsten arc welding on invar sheet
Manipulation of metal microstructures via welding technique has attracted many interests due to its various applications for microscopic electronic circuits and photo-electronic structures. Refilling deletion ...
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Article
Open AccessEffects of protein-enriched nutritional support on skeletal muscle mass and rehabilitative outcomes in brain tumor patients: a randomized controlled trial
Patients with brain tumors require extensive and prolonged rehabilitation efforts as they suffer from lesion-induced motor weakness as well as treatment-related side effects, often leading to a significant dec...
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Article
Open AccessFast reduction of Atlantic SST threatens Europe-wide gross primary productivity under positive and negative CO2 emissions
Climate change mitigation through negative CO2 emissions has been recognized as a crucial strategy to combat global warming. However, its potential effects on terrestrial productivity and agricultural activities ...
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Article
Tumor Pre-Targeting System Using Streptavidin-Expressing Bacteria
A major obstacle to targeted cancer therapy is identifying suitable targets that are specifically and abundantly expressed by solid tumors. Certain bacterial strains selectively colonize solid tumors and can d...
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Article
Open AccessClinical outcomes of colorectal neoplasm with positive resection margin after endoscopic submucosal dissection
A positive resection margin after colorectal endoscopic submucosal dissection (ESD) is associated with an increased risk of recurrence. We aimed to identify the clinical significance of positive resection marg...
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Article
Open AccessAnterior cingulate cortex-related functional hyperconnectivity underlies sensory hypersensitivity in Grin2b-mutant mice
Sensory abnormalities are observed in ~90% of individuals with autism spectrum disorders (ASD), but the underlying mechanisms are poorly understood. GluN2B, an NMDA receptor subunit that regulates long-term de...
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Article
Open AccessModeling acute myocardial infarction and cardiac fibrosis using human induced pluripotent stem cell-derived multi-cellular heart organoids
Heart disease involves irreversible myocardial injury that leads to high morbidity and mortality rates. Numerous cell-based cardiac in vitro models have been proposed as complementary approaches to non-clinica...
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Article
Multi-physics simulations for investigating the effect of electrode conditions on transscleral ocular iontophoresis for particulate drug delivery into ocular tissues
Transscleral ocular iontophoresis has been proposed to deliver charged particulate drugs to ocular tissues effectively by transmitting a weak electrical current through the sclera. The electric fields formed a...
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Article
Open AccessEfficacy of a new refractive multifocal contact lens for presbyopia
This prospective single-arm study aimed to evaluate the clinical efficacy and safety of a refractive multifocal contact lens for the correction of presbyopia in 22 patients. The participants underwent clinical...
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Article
Open AccessLoss of SREBP-1c ameliorates iron-induced liver fibrosis by decreasing lipocalin-2
Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis and is highly increased in nonalcoholic steatohepatitis (NASH). However, the molecula...
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Article
Accelerated life test of chemically strengthened light weight glass bottles by spray coating
This study investigated the strength retention and reliability of glass bottles through accelerated life tests in the presence and absence of chemical strengthening and hot end coating (HEC). Forced contact wa...
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Article
Open AccessThe Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
Mitophagy induction upon mitochondrial stress is critical for maintaining mitochondrial homeostasis and cellular function. Here, we found that Mst1/2 (Stk3/4), key regulators of the Hippo pathway, are required...
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Article
Open AccessDevelopment of finely tuned liposome nanoplatform for macrophage depletion
Immunotherapy with clodronate-encapsulated liposomes, which induce macrophage depletion, has been studied extensively. However, previously reported liposomal formulation-based drugs (Clodrosome® and m-Clodrosome®
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Article
Open AccessReal-world outcomes of third-line immune checkpoint inhibitors versus irinotecan-based chemotherapy in patients with advanced gastric cancer: a Korean, multicenter study (KCSG ST22-06)
Immune checkpoint inhibitor (ICI) or irinotecan-based chemotherapy is frequently used after failure of second-line paclitaxel plus ramucirumab treatment for patients with locally advanced unresectable or metas...
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Article
Open AccessSimultaneous determination of 31 Sulfonamide residues in various livestock matrices using liquid chromatography-tandem mass spectrometry
The widespread use of sulfonamides can result in the residue of sulfonamides in the foods of animal origin that are the major concerns of consumers and regulatory bodies due to their adverse reaction such as t...
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Article
Comparative metabolism of aschantin in human and animal hepatocytes
Aschantin, a tetrahydrofurofuran lignan with a 1,3-benzodioxole group derived from Flos Magnoliae, exhibits antioxidant, anti-inflammatory, cytotoxic, and antimicrobial activities. This study compared the metabol...
