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  1. Article

    Open Access

    SIRT1 ISGylation accelerates tumor progression by unleashing SIRT1 from the inactive state to promote its deacetylase activity

    ISG15 is an interferon-stimulated ubiquitin-like protein (UBL) with multifaceted roles as a posttranslational modifier in ISG15 conjugation (ISGylation). However, the mechanistic consequences of ISGylation in ...

    Ji An Kang, Yoon Jung Kim, Kyu Yun Jang, Hye Won Moon… in Experimental & Molecular Medicine (2024)

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  2. Article

    Open Access

    The diverse repertoire of ISG15: more intricate than initially thought

    ISG15, the product of interferon (IFN)-stimulated gene 15, is the first identified ubiquitin-like protein (UBL), which plays multifaceted roles not only as a free intracellular or extracellular molecule but al...

    Ji An Kang, Yoon Jung Kim, Young Joo Jeon in Experimental & Molecular Medicine (2022)

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  3. Article

    Open Access

    Interplay between 3′-UTR polymorphisms in the vascular endothelial growth factor (VEGF) gene and metabolic syndrome in determining the risk of colorectal cancer in Koreans

    Polymorphisms in angiogenesis-related genes and metabolic syndrome (MetS) risk factors play important roles in cancer development. Moreover, recent studies have reported associations between a number of 3′-UTR...

    Young Joo Jeon, Jong Woo Kim, Hye Mi Park, Hyo Geun Jang, Jung O Kim, Jisu Oh… in BMC Cancer (2014)

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