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Assessment of Temperature-Dependent Drug Release of Solubilizing Nanoformulations Using the SITUA
The evaluation of temperature-dependent drug release for solubilizing nanoformulations uses a modification of the stable isotope ultrafiltration assay (SITUA). This method is specific to parenterally administe...
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Article
Open AccessComparison of 2-octyl cyanoacrylate and n-octyl cyanoacrylate topical skin adhesives for wound closure after ankle fracture surgery: a prospective randomized trial
To date, only a few clinical studies have investigated the differences between 2-octyl cyanoacrylate and n-octyl cyanoacrylate topical skin adhesives (TSAs). This study aimed to compare the outcomes of the two TS...
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Article
Value of postoperative computed tomography for the diagnosis of lateral hinge fracture in medial opening-wedge supramalleolar osteotomy
It remains unclear whether computed tomography (CT) is superior to plain radiography in detecting lateral hinge fractures after medial opening-wedge supramalleolar osteotomy (SMO) of the ankle joint. This stud...
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Article
Learning curve of the Krackow suture technique for the repair of Achilles tendon rupture
Knowledge on the learning curve for the repair of Achilles tendon rupture is limited. The aim of this study was to quantify the learning curve for the Krackow suture technique for the repair of Achilles tendon...
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Article
Comparison between headless compression screws and tension band wires for the fixation of medial malleolar fractures: a prospective randomized trial
To date, there has been no prospective randomized trial supporting the rationale of the use of headless compression screw (HCS) compared to conventional fixation methods for medial malleolar fractures. This st...
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Article
How accurately can surgeons perform angle manipulation? Quantitative assessment of the accuracy of manual angle manipulation of orthopedic surgery: a cadaver study
To date, only few studies have been performed on the accuracy of manual angle manipulation during orthopedic surgery. This cadaver study was aimed at quantitatively assessing the accuracy of manual angle manip...
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Article
Open AccessIncidence and risk factor of allergic contact dermatitis to 2-octyl cyanoacrylate and n-butyl cyanoacrylate topical skin adhesives
Although the use of topical skin adhesives has increased as an alternative to conventional skin closure methods, studies on the incidence and risk factors of allergic contact dermatitis (ACD) to topical skin a...
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Article
Open AccessValidation and cross-cultural adaptation of the Korean translation of the Achilles tendon Total Rupture Score
The Achilles tendon Total Rupture Score (ATRS) is a widely used patient-reported outcome measure to assess clinical outcomes of Achilles tendon rupture, but it has not been validated in Korean yet. The purpose...
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Article
Model updating based on mixed-integer nonlinear programming under model-form uncertainty in finite element model
In this paper, a new finite element model updating (FEMU) method is proposed based on mixed-integer nonlinear programming (MINLP) to deal with model-form uncertainty in FE models. Depending on modelers’ prefer...
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Article
Age is a risk factor for contralateral tendon rupture in patients with acute Achilles tendon rupture
Rupture of the contralateral Achilles tendon following Achilles tendon rupture can lead to devastating outcomes. However, despite the clinical importance, the risk factors and incidence of contralateral Achill...
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Article
Achilles tendinosis does not always precede Achilles tendon rupture
Degenerative change is a typical histologic finding of Achilles tendinosis and is thought to be a factor associated with Achilles tendon rupture; however, this relationship remains controversial. Therefore, th...
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Article
Comparison of the use of evaporative coolants and ice packs for the management of preoperative edema and pain in ankle fractures: a prospective randomized controlled trial
The use of evaporative coolants in the management of acute musculoskeletal injury has received increasing attention recently. However, its efficacy compared with conventional cryotherapy in treating injured hu...
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Article
Open AccessPhylogenetic characterization of bacterial endophytes from four Pinus species and their nematicidal activity against the pine wood nematode
Recently, bacterial endophytes (BEs) have gained importance in the agricultural sector for their use as biocontrol agents to manage plant pathogens. Outbreak of the pine wilt disease (PWD) in Korea has led res...
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Article
Lateral column lengthening versus subtalar arthroereisis for paediatric flatfeet: a systematic review
This systematic review aimed to compare radiographic correction, clinical outcomes, complications, and re-operations between lateral column lengthening (LCL) and arthroereisis (AR) for treating symptomatic fla...
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Article
The predictive value of MRI in the syndesmotic instability of ankle fracture
Although many types of ankle fracture can be combined with syndesmosis injury, preoperative imaging studies rarely reveal instability of the syndesmosis. This study assessed the use of magnetic resonance imagi...
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Article
Open AccessPublisher Correction: Composition, diversity and bioactivity of culturable bacterial endophytes in mountain-cultivated ginseng in Korea
A correction to this article has been published and is linked from the HTML version of this paper. The error has been fixed in the paper.
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Article
Risk factors and the associated cutoff values for failure of corticosteroid injection in treatment of Morton’s neuroma
Understanding the risk factors that predict the prognosis of Morton’s neuroma after corticosteroid injection would help clinicians determine the appropriate treatment protocol. However, the cut-off values for ...
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Article
Open AccessFungal endophytes inhabiting mountain-cultivated ginseng (Panax ginseng Meyer): Diversity and biocontrol activity against ginseng pathogens
Fungal endophytes isolated from mountain-cultivated ginseng (MCG, Panax ginseng Meyer) were explored for their diversity and biocontrol activity against ginseng pathogens (Alternaria panax, Botrytis cinerea, Cyli...
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Article
Open AccessDJ-1 controls bone homeostasis through the regulation of osteoclast differentiation
Receptor activator of NF-kB ligand (RANKL) generates intracellular reactive oxygen species (ROS), which increase RANKL-mediated signaling in osteoclast (OC) precursor bone marrow macrophages (BMMs). Here we sh...
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Article
Open AccessComposition, diversity and bioactivity of culturable bacterial endophytes in mountain-cultivated ginseng in Korea
Plants harbor diverse communities of bacterial species in their internal compartments. Here we isolated and identified bacterial endophytes from mountain-cultivated ginseng (MCG, Panax ginseng Meyer) to make work...