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Article
A catalytic process enables efficient and programmable access to precisely altered indole alkaloid scaffolds
A compound’s overall contour impacts its ability to elicit biological response, rendering access to distinctly shaped molecules desirable. A natural product’s framework can be modified, but only if it is abund...
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Article
Specific Knockdown of the NDUFS4 Gene Reveals Important Roles of Ferroptosis in UVB-induced Photoaging
Ultraviolet (UV) irradiation significantly contributes to photoaging. Ferroptosis, an iron-dependent cell death mode recently identified, plays a key role in UVB-induced skin photoaging. This study examines th...
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Article
Open AccessConstruction of a novel prognostic model in skin cutaneous melanoma based on chemokines-related gene signature
Skin cutaneous melanoma, SKCM, is one of the most aggressive treatment-resistant tumours. Despite the fact that the BRAF oncogene and immunological checkpoints such as PD-1/PD-L1 and CTLA-4 have enhanced the t...
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Article
Visible light promoted synthesis of N-aroylsulfoximines by oxidative C-H acylation of NH-sulfoximines
The visible light-promoted synthesis of N-aroylsulfoximines has been accomplished via an oxidative dehydrogenative coupling at room temperature under air without the addition of a photosensitizer, metal catalyst,...
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Article
Isolated Cutaneous Granuloma Caused by Candida glabrata: A Rare Case Report and Literature Review
The incidence of candidiasis due to non-albicans Candida species (especially Candida glabrata) has significantly increased in recent decades. Candida glabrata often invades immunocompromised hosts and causes syst...
