3 Result(s)
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Article
Open AccessPhf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
Epigenomic abnormalities caused by genetic mutation in epigenetic regulators can result in neurodevelopmental disorders, deficiency in neural plasticity and mental retardation. As a histone demethylase, plant ...
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Article
Open AccessSystemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
Sepsis, during which the intestinal epithelial barrier is frequently disrupted, remains a challenging and life-threatening problem in clinical practice. The P2X7 receptor (P2X7R) is a non-selective adenosine t...
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Article
Open AccessInjectable in situ cross-linking chitosan-hyaluronic acid based hydrogels for abdominal tissue regeneration
Abdominal wall defect caused by open abdomen (OA) or abdominal trauma is a serious issue since it induces several clinical problems. Although a variety of prosthetic materials are commonly employed, complicati...
