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Article
Correction to: Combined viral quasispecies diversity and hepatitis B core-related antigen predict off-nucleos(t)ide analog durability in HBeAg-negative patients
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Article
Combined viral quasispecies diversity and hepatitis B core-related antigen predict off-nucleos(t)ide analog durability in HBeAg-negative patients
Viral quasispecies dynamics between pre- and post-nucleos(t)ide analog (NA) therapy remains unclear.
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Article
Open AccessHBV X protein-based therapeutic vaccine accelerates viral antigen clearance by mobilizing monocyte infiltration into the liver in HBV carrier mice
Hepatitis B virus (HBV) persistently infected about 250 million people worldwide, and a curative treatment remains an unmet medical need. Among many approaches to treat chronic hepatitis B (CHB), therapeutic v...
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Article
Open AccessDe novo assembly of highly polymorphic metagenomic data using in situ generated reference sequences and a novel BLAST-based assembly pipeline
The accuracy of metagenomic assembly is usually compromised by high levels of polymorphism due to divergent reads from the same genomic region recognized as different loci when sequenced and assembled together...
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Article
Synthesis and anti-cancer activity of a glycosyl library of \(\varvec{N}\) -acetylglucosamine-bearing oleanolic acid
N-Acetylglucosamine-bearing triterpenoid saponins (GNTS) were reported to be a unique type of saponins with potent anti-tumor activity. In order to study the structure–activity relationship of GN...
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Article
Open AccessFosmid library end sequencing reveals a rarely known genome structure of marine shrimp Penaeus monodon
The black tiger shrimp (Penaeus monodon) is one of the most important aquaculture species in the world, representing the crustacean lineage which possesses the greatest species diversity among marine invertebrate...
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Article
Single cell transcriptome analysis upon MCF-7 breast cancer