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    Article

    A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation

    Histone modifications induced by activated signalling cascades are crucial to cell-lineage decisions. Osteoblast and adipocyte differentiation from common mesenchymal stem cells is under transcriptional contro...

    Ichiro Takada, Masatomo Mihara, Miyuki Suzawa, Fumiaki Ohtake in Nature Cell Biology (2007)

  2. Article

    Erratum: A histone lysine methyltransferase activated by non-canonical Wnt signalling supresses PPAR-γ transactivation

    Nat. Cell Biol. 9, 1273–1285 (2007); published online 21st October 2007 In the version of this Article initially published, Figs 6a and 6c contained panels that were inadvertently duplicated. In Fig. 6a, the p...

    Ichiro Takada, Masatomo Mihara, Miyuki Suzawa, Fumiaki Ohtake in Nature Cell Biology (2012)

  3. Article

    Retraction Note: A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-γ transactivation

    Although the authors believe that the key finding and conclusions are still valid, recently detected image manipulation in the published figures undermines their full confidence in the integrity of the study. ...

    Ichiro Takada, Masatomo Mihara, Miyuki Suzawa, Fumiaki Ohtake in Nature Cell Biology (2014)

  4. No Access

    Article

    Biochemical and histochemical analyses of lecithin:retinol acyltransferase from polar bear (Ursus maritimus) livers

    Vitamin A is a fat-soluble vitamin required for many physiological functions. It is known that polar bears (Ursus maritimus) store a large amount of vitamin A within hepatic stellate cells (HSCs). However, the mo...

    Yoshihiro Mezaki, Keisuke Nagatsuma, Hiroshi Yokoyama, Jong Hyuk Park in Polar Biology (2018)

  5. Article

    Open Access

    Bio-artificial bone formation model with a radial-flow bioreactor for implant therapy—comparison between two cell culture carriers: porous hydroxyapatite and β-tricalcium phosphate beads

    Bone grafting is necessary before dental implant treatment in patients with jaw bone defects. Currently, autologous bone grafting is a major burden on the patient. However, it is impossible to form a sufficien...

    Hideki Nomoto, Haruka Maehashi, Misako Shirai, Mariko Nakamura in Human Cell (2019)

  6. Article

    Open Access

    Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4

    Cell lines are powerful tools for research into liver function at the molecular level. However, they are generally unsuitable for rigorously assessing the effects of amino acid composition, because many lines ...

    Takahiko J. Fujimi, Yoshihiro Mezaki, Takahiro Masaki, Ayasa Tajima in Human Cell (2020)