103 Result(s)
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Yoshihiro Matsumoto
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In Situ Observation of the Decomposition Process of Woodchips in Subcritical- and Supercritical Water by Neutron Imaging
In situ observation of the decomposition process of woodchips (cedar and Quercus acutissima) in subcritical- and supercritical water was performed by neutron imaging experiment. The woodchips and D2O were sealed ...
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Open AccessRadiographic knee osteoarthritis severity has no impact on fall risk: the locomotive syndrome and health outcomes in the aizu cohort study (LOHAS): a cross-sectional study
To investigate factors that have an impact on the risk of falls and determine whether radiographic knee osteoarthritis (KOA) is a factor involved in falls independent of knee pain, psychological factors, and p...
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Open AccessImmune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8+ T cell infiltration
Leiomyosarcomas are among the most common histological types of soft tissue sarcoma (STS), with no effective treatment available for advanced patients. Lung metastasis, the most common site of distant metastas...
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Open AccessExperimental visualization of water/ice phase distribution at cold start for practical-sized polymer electrolyte fuel cells
The automotive industry aims to ensure the cold-start capability of polymer electrolyte fuel cells (PEFCs) for develo** fuel cell electric vehicles that can be driven in cold climates. Water and ice behavior...
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Efficacy and Safety of Adjuvant Radiotherapy for Soft Tissue Sarcoma: A Two-Institution Retrospective Observational Study
The recommended post-operative radiotherapy dose of approximately 60 Gy may be reduced during treatment planning, and the optimal irradiation method and dose remain unclear. We aimed to clarify the usefulness ...
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Open AccessViable tumor cell density after neoadjuvant chemotherapy assessed using deep learning model reflects the prognosis of osteosarcoma
Prognosis after neoadjuvant chemotherapy (NAC) for osteosarcoma is generally predicted using manual necrosis-rate assessments; however, necrosis rates obtained in these assessments are not reproducible and do ...
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Open AccessIn situ neutron imaging of lithium-ion batteries during heating to thermal runaway
Lithium-ion batteries (LIBs) have become essential components that power most current technologies, such as smartphones and electric vehicles, thus making various safety evaluations necessary to ensure their s...
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Open AccessMacrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis
After spinal cord injury (SCI), inflammatory cells such as macrophages infiltrate the injured area, and astrocytes migrate, forming a glial scar around macrophages. The glial scar inhibits axonal regeneration,...
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Clinical significance of signal regulatory protein alpha and T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domain expression in undifferentiated pleomorphic sarcoma
Undifferentiated pleomorphic sarcoma (UPS) is associated with poor prognosis. Recently, signal regulatory protein alpha (SIRPα), which is the immune checkpoint of macrophages, and T cell immunoreceptor with im...
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Open AccessCorrection: The insoluble excretion of multi-matrix system mesalazine preparations in patients with ulcerative colitis
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Open AccessDistinct gene signatures of monocytes and B cells in patients with giant cell arteritis: a longitudinal transcriptome analysis
Giant cell arteritis (GCA) is a primary large-vessel vasculitis (LVV) of unknown origin. Its management is a challenge due to the late onset of disease symptoms and frequent relapse; therefore, clarifying the ...
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First-line pembrolizumab for patients with early relapsing urothelial carcinoma after perioperative chemotherapy: a retrospective analysis of bladder cancer and upper urinary tract cancer
First-line pembrolizumab is available for recurrent disease within 12 months after the receipt of platinum-based perioperative chemotherapy. However, the benefit of first-line pembrolizumab is unclear. This st...
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Open AccessPerioperative Adriamycin plus ifosfamide vs. gemcitabine plus docetaxel for high-risk soft tissue sarcomas: randomised, phase II/III study JCOG1306
This randomised phase II/III trial aimed to determine whether perioperative chemotherapy with gemcitabine plus docetaxel (GD) is non-inferior to the standard Adriamycin plus ifosfamide (AI) in terms of overall...
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Open AccessPostoperative clinical and functional outcomes in patients with tumor and tumor-like lesion of foot and ankle
Tumors and tumor-like lesions of the foot and ankle are relatively rare and their postoperative clinical outcome has not been well reported.
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Open AccessZinc chelator treatment in crush syndrome model mice attenuates ischemia–reperfusion-induced muscle injury due to suppressing of neutrophil infiltration
In crush syndrome, massive muscle breakdown resulting from ischemia–reperfusion muscle injury can be a life-threatening condition that requires urgent treatment. Blood reperfusion into the ischemic muscle trig...
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Open AccessThe insoluble excretion of multi-matrix system mesalazine preparations in patients with ulcerative colitis
Multi-matrix mesalazine (MMX) is an important treatment for ulcerative colitis (UC); however, it is often excreted intact, which increases the risk of relapse. This study aimed to clarify the risk factors for ...
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Open AccessNuclear β-catenin translocation plays a key role in osteoblast differentiation of giant cell tumor of bone
Denosumab is a game-changing drug for giant cell tumor of bone (GCTB); however, its clinical biomarker regarding tumor ossification of GCTB has not been elucidated. In this study, we investigated the relations...
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Open AccessIbandronate Suppresses Changes in Apatite Orientation and Young's Modulus Caused by Estrogen Deficiency in Rat Vertebrae
Bone material quality is important for evaluating the mechanical integrity of diseased and/or medically treated bones. However, compared to the knowledge accumulated regarding changes in bone mass, our underst...
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Methylation-mediated silencing of protein kinase C zeta induces apoptosis avoidance through ATM/CHK2 inactivation in dedifferentiated chondrosarcoma
Dedifferentiated chondrosarcoma (DDCS) is an aggressive bone tumour with a poor prognosis and no effective treatment. Because changes in DNA methylation play critical roles in DDCS, we explored the roles that ...
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Open AccessAdaptive antitumor immune response stimulated by bio-nanoparticle based vaccine and checkpoint blockade
Interactions between tumor and microenvironment determine individual response to immunotherapy. Triple negative breast cancer (TNBC) and hepatocellular carcinoma (HCC) have exhibited suboptimal responses to im...
