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Recent Advances on Solution-phase Synthesis of Metal Chalcohalide Nanocrystals
Chalcohalide nanocrystals have attracted significant attention as promising candidates for the fabrication of novel electronic and optoelectronic devices. Chalcohalide exhibit high charge carrier mobility, def...
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Open AccessThe identification of effective tumor-suppressing neoantigens using a tumor-reactive TIL TCR-pMHC ternary complex
Neoantigens are ideal targets for cancer immunotherapy because they are expressed de novo in tumor tissue but not in healthy tissue and are therefore recognized as foreign by the immune system. Advances in nex...
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Open AccessMental health effects associated with COVID-19 financial assistance in South Korea: a comparison of employment status
COVID-19 has created tensions across different sectors of the society, but the impact has been unequal. Vulnerable people have been most affected, especially those with insecure employment and who have experie...
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Open AccessColloidal inorganic nano- and microparticles for passive daytime radiative cooling
Compared to traditional cooling systems, radiative cooling (RC) is a promising cooling strategy in terms of reducing energy consumption enormously and avoiding severe environmental issues. Radiative cooling ma...
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Protocol
Computational Identification and Design of Complementary β-Strand Sequences
The ß-sheet is a regular secondary structure element which consists of linear segments called ß-strands. They are involved in many important biological processes, and some are known to be related to serious di...
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Open AccessDeimmunization of flagellin for repeated administration as a vaccine adjuvant
Flagellin, a protein-based Toll-like receptor agonist, is a versatile adjuvant applicable to wide spectrum of vaccines and immunotherapies. Given reiterated treatments of immunogenic biopharmaceuticals should ...
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EpiSweep: Computationally Driven Reengineering of Therapeutic Proteins to Reduce Immunogenicity While Maintaining Function
Therapeutic proteins are yielding ever more advanced and efficacious new drugs, but the biological origins of these highly effective therapeutics render them subject to immune surveillance within the patient’s...
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Computationally driven deletion of broadly distributed T cell epitopes in a biotherapeutic candidate
Biotherapeutics are subject to immune surveillance within the body, and anti-biotherapeutic immune responses can compromise drug efficacy and patient safety. Initial development of targeted antidrug immune me...
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Chapter
Protein Modeling and Structural Prediction
Proteins perform crucial functions in every living cell. The genetic information in every organismʼs DNA encodes the proteinʼs amino acid sequence, which determines its three-dimensional structure, which,...
