10 Result(s)

Article

Precise single column resection and reconstruction with femoral head plus total hip replacement for primary malignant peri-acetabulum tumors

To evaluate whether single acetabular column can be reserved and the effect of reconstruction with femoral head plus total hip replacement (THR) for primary malignant peri-acetabulum tumors. From 2007 to 2015,...

Yongkun Yang, Yuan Li, Weifeng Liu, **aohui Niu in Scientific Reports (2024)

Article

Genomic and transcriptomic characterization of pre-operative chemotherapy response in patients with osteosarcoma

Osteosarcoma is a heterogeneous disease with regard to its chemotherapy response and clinical outcomes. This study aims to investigate the genomic and transcriptomic characteristics related to pre-operative ch...

Yongkun Yang, Zhen Huang, Mingming Yuan, **qiu Rui, Rongrong Chen… in Scientific Reports (2023)

Article

Metastasis-Related Signature for Clinically Predicting Prognosis and Tumor Immune Microenvironment of Osteosarcoma Patients

Osteosarcoma is the most prevalent clinical malignant bone tumor in adolescents. The prognosis of metastatic osteosarcoma is still very poor. The aim of our study was to investigate the clinical diagnosis and ...

Qing Zhang, Zhi** Deng, Yongkun Yang in Molecular Biotechnology (2023)

Article

Preclinical development and evaluation of nanobody-based CD70-specific CAR T cells for the treatment of acute myeloid leukemia

Acute myeloid leukemia (AML) treatment remains challenging. CD70 was reported as a promising AML-specific antigen. Preclinically, CAR T-cell with single-chain-variable fragment (scFv) or truncated CD27 targeti...

Jiali Cheng, Tong Ge, **aojian Zhu, Jue Wang… in Cancer Immunology, Immunotherapy (2023)

Article

A novel full-human CD22-CAR T cell therapy with potent activity against CD22^low B-ALL

Yue Tan, Haodong Cai, Chuo Li, Bi** Deng, Weiliang Song… in Blood Cancer Journal (2021)

Article

Mesh patch and anchors can improve clinical results of prosthetic replacement after resection of primary proximal humerus malignant tumor

The purpose of this study was to evaluate the functional results, complications and related factors of prosthesis reconstruction after malignant tumor resection of primary proximal humeral, and also evaluate w...

Yongkun Yang, Yuan Li, Weifeng Liu, **aohui Niu in Scientific Reports (2021)

Article

The biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platforms

Because of the need to limit side-effects, nanoparticles are increasingly being studied as drug-carrying and targeting tools. We have previously reported on a scheme to produce protein-based self-assembling na...

Yongkun Yang, Tobias Neef, Christian Mittelholzer… in Journal of Nanobiotechnology (2013)

Article

Erratum to: Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

Margaret E McCoy, Hannah E Golden, Tais APF Doll, Yongkun Yang… in Malaria Journal (2013)

Article

Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine

A lack of defined correlates of immunity for malaria, combined with the inability to induce long-lived sterile immune responses in a human host, demonstrate a need for improved understanding of potentially pro...

Margaret E McCoy, Hannah E Golden, Tais APF Doll, Yongkun Yang… in Malaria Journal (2013)

Article

Encapsulation of gold nanoparticles into self-assembling protein nanoparticles

Gold nanoparticles are useful tools for biological applications due to their attractive physical and chemical properties. Their applications can be further expanded when they are functionalized with biological...

Yongkun Yang, Peter Burkhard in Journal of Nanobiotechnology (2012)