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Article
Open AccessPrecise single column resection and reconstruction with femoral head plus total hip replacement for primary malignant peri-acetabulum tumors
To evaluate whether single acetabular column can be reserved and the effect of reconstruction with femoral head plus total hip replacement (THR) for primary malignant peri-acetabulum tumors. From 2007 to 2015,...
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Article
Open AccessGenomic and transcriptomic characterization of pre-operative chemotherapy response in patients with osteosarcoma
Osteosarcoma is a heterogeneous disease with regard to its chemotherapy response and clinical outcomes. This study aims to investigate the genomic and transcriptomic characteristics related to pre-operative ch...
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Article
Open AccessMetastasis-Related Signature for Clinically Predicting Prognosis and Tumor Immune Microenvironment of Osteosarcoma Patients
Osteosarcoma is the most prevalent clinical malignant bone tumor in adolescents. The prognosis of metastatic osteosarcoma is still very poor. The aim of our study was to investigate the clinical diagnosis and ...
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Article
Effect of Zr Treatment on Inclusion and Solidification Microstructure in Ti Deoxidized Low Carbon Microalloyed Steel
Inclusion-induced acicular ferrite (AF) is a preferred microstructure that could refine grains and improve strength and toughness. As a prerequisite, the effective inclusions generated by the optimal range of ...
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Article
Open AccessPreclinical development and evaluation of nanobody-based CD70-specific CAR T cells for the treatment of acute myeloid leukemia
Acute myeloid leukemia (AML) treatment remains challenging. CD70 was reported as a promising AML-specific antigen. Preclinically, CAR T-cell with single-chain-variable fragment (scFv) or truncated CD27 targeti...
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Article
Research on Inclusion Evolution during Re-Heating Process in Ti-Zr Deoxidized Low Carbon Steel
The effect of the re-heating process on inclusion evolution in Ti-Zr deoxidized low carbon steel was investigated using high-temperature resistance furnace, high-temperature confocal laser scanning microscope,...
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Article
Open AccessA novel full-human CD22-CAR T cell therapy with potent activity against CD22low B-ALL
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Article
A novel LRRFIP1-ALK fusion in inflammatory myofibroblastic tumor of hip and response to crizotinib
An inflammatory myofibroblastic tumor (IMT) is a rare invasive soft tissue mass with intramuscular penetration that is primarily treated via a surgical procedure. However, with unclear boundaries and a high ra...
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Article
Open AccessMesh patch and anchors can improve clinical results of prosthetic replacement after resection of primary proximal humerus malignant tumor
The purpose of this study was to evaluate the functional results, complications and related factors of prosthesis reconstruction after malignant tumor resection of primary proximal humeral, and also evaluate w...
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Article
Evolution of Microstructures and Mechanical Properties of Zr-Containing Y-CLAM During Thermal Aging
The thermal stability and mechanical properties of China low activation martensitic steel with Zr and Y were investigated via thermal aging at 550 °C for 8000 h. The Laves phase content monotonically increased...
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Article
Coupling Effect of Prior Austenite Grain Size and Inclusion Characteristics on Acicular Ferrite Formation in Ti-Zr Deoxidized Low Carbon Steel
The coupling effect of prior austenite grain size and inclusion characteristics on acicular ferrite (AF) formation was investigated in Ti-Zr deoxidized low carbon steel by utilizing the high temperature confoc...
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Article
Effects of Yttrium and Heat Treatment on the Microstructure and Mechanical Properties of CLAM Steel
The effects of normalizing and tempering temperatures on the microstructures and mechanical properties of China Low Activation Martensitic (CLAM) steel with and without yttrium were studied. Based on the optim...
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Article
In Situ Observation of Acicular Ferrite Nucleation and Growth at Different Cooling Rate in Ti-Zr Deoxidized Steel
The effects of cooling rate on acicular ferrite (AF) nucleation, growth, and inclusion characteristics in Ti-Zr deoxidation steel were studied by utilizing the high temperature confocal laser scanning microsco...
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Article
Recurrence and survival factors analysis of 171 cases of sacral chordoma in a single institute
To evaluate postoperative recurrence, survival and metastasis results and related factors of sacral chordoma.
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Chapter and Conference Paper
Simulation Study on Direct Desulfurization of Molten Iron by Magnesium Vapor
A new technique of bottom blown method was proposed for desulfurization of molten iron, which uses inert gas to carry and combines with mechanical stirring. A water model was established based on the similar...
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Article
Open AccessThe biodistribution of self-assembling protein nanoparticles shows they are promising vaccine platforms
Because of the need to limit side-effects, nanoparticles are increasingly being studied as drug-carrying and targeting tools. We have previously reported on a scheme to produce protein-based self-assembling na...
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Article
Open AccessErratum to: Mechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine
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Article
Open AccessMechanisms of protective immune responses induced by the Plasmodium falciparum circumsporozoite protein-based, self-assembling protein nanoparticle vaccine
A lack of defined correlates of immunity for malaria, combined with the inability to induce long-lived sterile immune responses in a human host, demonstrate a need for improved understanding of potentially pro...
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Article
Open AccessEncapsulation of gold nanoparticles into self-assembling protein nanoparticles
Gold nanoparticles are useful tools for biological applications due to their attractive physical and chemical properties. Their applications can be further expanded when they are functionalized with biological...
