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  1. Article

    Open Access

    Development of a packaging cell line for propagation of replication-deficient adenovirus vector

    A human embryonic kidney cell line 293 is widely used for adenovirus production and propagation. With this cell line, however, replication-competent virus (RCV) is frequently generated, especially during large...

    Jong-Sik Kim, Seung-Hoon Lee, Yong-Suk Cho in Experimental & Molecular Medicine (2001)