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  1. Article

    Open Access

    miRNA-206-3p alleviates LPS-induced acute lung injury via inhibiting inflammation and pyroptosis through modulating TLR4/NF-κB/NLRP3 pathway

    Acute lung injury (ALI) is life-threatening. MicroRNAs (miRNAs) are often abnormally expressed in inflammatory diseases and are closely associated with ALI. This study investigates whether miRNA-206-3p attenua...

    Mengchi Chen, **gfeng Zhang, Hongyuan Huang, Zichen Wang, Yong Gao in Scientific Reports (2024)

  2. Article

    Open Access

    Stem Leydig cells support macrophage immunological homeostasis through mitochondrial transfer in mice

    As testicular mesenchymal stromal cells, stem Leydig cells (SLCs) show great promise in the treatment of male hypogonadism. The therapeutic functions of mesenchymal stromal cells are largely determined by thei...

    Ani Chi, Bicheng Yang, Hao Dai, **nyu Li, Jiahui Mo, Yong Gao in Nature Communications (2024)

  3. Article

    Open Access

    Experimentally validated design principles of heteroatom-doped-graphene-supported calcium single-atom materials for non-dissociative chemisorption solid-state hydrogen storage

    Non-dissociative chemisorption solid-state storage of hydrogen molecules in host materials is promising to achieve both high hydrogen capacity and uptake rate, but there is the lack of non-dissociative hydroge...

    Yong Gao, Zhenglong Li, Pan Wang, Wen-Gang Cui, **aowei Wang in Nature Communications (2024)

  4. Article

    Open Access

    Cyclic loading changes the taproot's tensile properties and reinforces the soil via the shrub's taproot in semi-arid areas, China

    This study aimed to reveal the soil reinforcement by shrub root systems after repeated stress from external forces, such as high winds and runoff, for extended periods in the wind-hydraulic compound erosion zo...

    **ghua Hu, **n Zhang, Maolin Yan, Luyi Bai, Shusen Wang, Bo Wang in Scientific Reports (2024)

  5. Article

    Open Access

    Gradient design of imprinted anode for stable Zn-ion batteries

    Achieving long-term stable zinc anodes at high currents/capacities remains a great challenge for practical rechargeable zinc-ion batteries. Herein, we report an imprinted gradient zinc electrode that integrate...

    Qinghe Cao, Yong Gao, Jie Pu, **n Zhao, Yuxuan Wang, Jipeng Chen in Nature Communications (2023)

  6. Article

    Open Access

    Identification of immune-related subtypes of colorectal cancer to improve antitumor immunotherapy

    Immunotherapy involving immune checkpoint inhibitors (ICIs) for enhancing immune system activation is promising for tumor management. However, the patients’ responses to ICIs are different. Here, we applied a ...

    **aobo Zheng, Yong Gao, Chune Yu, Guiquan Fan, Pengwu Li, Ming Zhang in Scientific Reports (2021)

  7. Article

    Open Access

    Neck circumference and waist circumference associated with cardiovascular events in type 2 diabetes (Bei**g Community Diabetes Study 23)

    Obesity increases the risk of develo** cardiovascular disease and other metabolic diseases. We intended to compare three different anthropometric indicators of obesity, in predicting the incidence of cardiov...

    Guang-Ran Yang, Ming-**a Yuan, Gang Wan, Xue-Lian Zhang, Han-**g Fu in Scientific Reports (2021)

  8. Article

    Open Access

    Author Correction: Effects of Compound Sand Barrier for Habitat Restoration on Sediment Grain-size Distribution in Ulan Buh Desert

    An amendment to this paper has been published and can be accessed via a link at the top of the paper.

    **a Pan, Zhenyi Wang, Yong Gao in Scientific Reports (2020)

  9. Article

    Open Access

    Heavy N+ ion transfer in doubly charged N2Ar van der Waals cluster

    Van der Waals clusters are weakly bound atomic/molecular systems and are an important medium for understanding micro-environmental chemical phenomena in bio-systems. The presence of neighboring atoms may open ...

    **aoLong Zhu, **aoQing Hu, ShunCheng Yan, YiGeng Peng in Nature Communications (2020)

  10. Article

    Open Access

    Effects of Compound Sand Barrier for Habitat Restoration on Sediment Grain-size Distribution in Ulan Buh Desert

    Wind erosion is a huge challenge for ecologists to stabilize sand dunes and to change them into stable productive ecosystems. In order to better understand its role in the process of ecological restoration, th...

    **a Pan, Zhenyi Wang, Yong Gao in Scientific Reports (2020)

  11. Article

    Open Access

    Hypothalamus-pituitary-gonad axis transcriptome profiling for sex differentiation in Acipenser sinensis

    Chinese sturgeon (Acipenser sinensis), a critically endangered Acipenseridae family member, is one of the largest anadromous, native fish in China. Numerous research programmes and protection agencies have focuse...

    Hejun Du, Jianbo Jian, Binzhong Wang, Xueqing Liu, Jianwei Chen in Scientific Data (2019)

  12. Article

    Open Access

    Genome-wide Identification of Jatropha curcas MAPK, MAPKK, and MAPKKK Gene Families and Their Expression Profile Under Cold Stress

    Mitogen-activated protein kinase (MAPK) cascades are fundamental signal transduction modules in all eukaryotic organisms, controlling cell division, growth, development, and hormone signaling. Additionally, th...

    Haibo Wang, Ming Gong, Junyun Guo, Hu **n, Yong Gao, Chao Liu in Scientific Reports (2018)

  13. Article

    Open Access

    A meta-analysis of Prognostic factor of Pancreatic neuroendocrine neoplasms

    Pancreatic neuroendocrine neoplasms (pNENs) are a group of clinically rare and heterogeneous diseases of the pancreas. However, the prognostic factors for this disease in patients still remain controversial. T...

    Yong Gao, Hao Gao, Guangfu Wang, Lingdi Yin, Wenbin Xu, Yunpeng Peng in Scientific Reports (2018)

  14. Article

    Open Access

    Adrenomedullin protects Leydig cells against lipopolysaccharide-induced oxidative stress and inflammatory reaction via MAPK/NF-κB signalling pathways

    This study aimed to explore the possible benefits of adrenomedullin (ADM) in preventing oxidative stress and inflammation by using an in vitro primary culture model of rat Leydig cells exposed to lipopolysacchari...

    Wei Hu, Lei Shi, Ming-yong Li, Pang-hu Zhou, Bo Qiu, Ke Yin in Scientific Reports (2017)

  15. Article

    Open Access

    Genetic diversity and structure of wild and cultivated Amorphophallus paeoniifolius populations in southwestern China as revealed by RAD-seq

    Amorphophallus paeoniifolius, is a commercially important vegetable crop because of its high production potential. In this study, we generated a total of 166 Gb of genomic data from 16 wi...

    Yong Gao, Si Yin, Lifang Wu, Dongqin Dai, Haibo Wang, Chao Liu in Scientific Reports (2017)

  16. Article

    Open Access

    Multi-factors including Inflammatory/Immune, Hormones, Tumor-related Proteins and Nutrition associated with Chronic Prostatitis NIH IIIa+b and IV based on FAMHES project

    Chronic prostatitis (CP) is a complex disease. Fragmentary evidence suggests that factors such as infection and autoimmunity might be associated with CP. To further elucidate potential risk factors, the curren...

    Yang Chen, Jie Li, Yanling Hu, Haiying Zhang, **aobo Yang in Scientific Reports (2017)

  17. Article

    Open Access

    Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression

    The RTK/ERK signaling pathway has been implicated in prostate cancer progression. However, the genetic relevance of this pathway to aggressive prostate cancer at the SNP level remains undefined. Here we perfor...

    Yang Chen, Qin Zhang, Qiuyan Wang, Jie Li, Csilla Sipeky, Jihan **a in Scientific Reports (2017)

  18. Article

    Open Access

    The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

    Protease nexin-1 (PN-1) is a serine protease inhibitor belonging to the serpin superfamily. This study was undertaken to investigate the regulatory role of PN-1 in the pathogenesis of intervertebral disk (IVD)...

    **nghuo Wu, Wei Liu, Zhenfeng Duan, Yong Gao, Shuai Li, Kun Wang in Scientific Reports (2016)

  19. Article

    Open Access

    Existence detection and embedding rate estimation of blended speech in covert speech communications

    Covert speech communications may be used by terrorists to commit crimes through Internet. Steganalysis aims to detect secret information in covert communications to prevent crimes. Herein, based on the average...

    Lijuan Li, Yong Gao in SpringerPlus (2016)

  20. Article

    Open Access

    A Facile and Low-Cost Route to Heteroatom Doped Porous Carbon Derived from Broussonetia Papyrifera Bark with Excellent Supercapacitance and CO2 Capture Performance

    In this work, we present a facile and low-cost approach to synthesize heteroatom doped porous carbon via hydrothermal treatment of stem bark of broussonetia papyrifera (BP) as the biomass precursor in diluted ...

    Tongye Wei, Qi Zhang, **aolin Wei, Yong Gao, Huaming Li in Scientific Reports (2016)

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