18 Result(s)
within
Yong Lin
Life Sciences
English
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Article
Effect of low-temperature stress on transcriptome and Na+/K+-ATPase changes in Oreochromis niloticus gill tissues
Low temperatures limit the development of Oreochromis niloticus (tilapia), and an increase in low-temperature tolerance would increase yields. We studied the responses of tilapia to low temperatures. The fish wer...
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Open AccessTargeting the SOX2/CDP protein complex with a peptide suppresses the malignant progression of esophageal squamous cell carcinoma
Emerging evidence indicates that SOX2 is an oncogene for esophageal squamous cell carcinoma (ESCC). However, direct targeting of SOX2 is not feasible given that this transcription factor plays important roles ...
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Open AccessMicroRNA-148a-3p suppresses cell proliferation and migration of esophageal carcinoma by targeting CEP55
This study evaluated microRNA-148a-3p in esophageal carcinoma cells. The prediction of bioinformatics analysis revealed that microRNA-148a-3p may target CEP55. qRT-PCR and western blot showed that CEP55 level ...
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Open AccessOver-expression of lncRNA TMEM161B-AS1 promotes the malignant biological behavior of glioma cells and the resistance to temozolomide via up-regulating the expression of multiple ferroptosis-related genes by sponging hsa-miR-27a-3p
A growing body of evidence suggests that long-chain non-coding RNA (lncRNA) plays an important role in the malignant biological behavior and drug resistance of glioblastoma (GBM) cells. In this study, we analy...
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Open AccessmiR-29a sensitizes the response of glioma cells to temozolomide by modulating the P53/MDM2 feedback loop
Recently, pivotal functions of miRNAs in regulating common tumorigenic processes and manipulating signaling pathways in brain tumors have been recognized; notably, miR‐29a is closely associated with p53 signal...
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Open AccessThe SARS-CoV-2 protein ORF3a inhibits fusion of autophagosomes with lysosomes
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the ongoing coronavirus disease 2019 pandemic. How SARS-CoV-2 regulates cellular responses to escape clearance by host cells is unknown. ...
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Open AccessIdentification of a quantitative trait loci (QTL) associated with ammonia tolerance in the Pacific white shrimp (Litopenaeus vannamei)
Ammonia is one of the most common toxicological environment factors affecting shrimp health. Although ammonia tolerance in shrimp is closely related to successful industrial production, few genetic studies of ...
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Open AccessHepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components
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Open AccessProteomic analysis of the inhibitory effect of epigallocatechin gallate on lipid accumulation in human HepG2 cells
(−)-Epigallocatechin-3-gallate (EGCG), the most abundant catechin found in green tea, effectively reduces body weight and tissue and blood lipid accumulation. To explore the mechanism by which EGCG inhibits ce...
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Shotgun proteomics and network analysis of ubiquitin-related proteins from human breast carcinoma epithelial cells
Protein ubiquitination via the covalent attachment of ubiquitin (Ub) plays an important role in the regulation of the stability, function or localization of multiple proteins in eukaryotic cells. Comprehensive...
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Article
QSAR Study on Insect Neuropeptide Potencies Based on a Novel Set of Parameters of Amino Acids by Using OSC-PLS Method
The potencies of natural adipokinetic hormones and synthetic variants (short peptides) have been obtained in Locusta migratoria. This short peptides (a total of sixty-nine analogues) data was used to construct th...
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Article
Quantitative Structure–Activity Relationship Model for Prediction of Protein–Peptide Interaction Binding Affinities between Human Amphiphysin-1 SH3 Domains and Their Peptide Ligands
Protein–protein interaction plays a critical role in signal transduction and many other key biological processes. The present study evaluated four parameters selected from among 554 physiochemical variables of...
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Article
Proteomics analysis of plasma membrane from liver sinusoidal endothelial cells after partial hepatectomy by an improved two-dimensional electrophoresis
Liver regeneration is an angiogenesis-associated phenomenon. To identify key plasma membrane (PM) proteins of endothelial cells involved in the initiation of angiogenesis during liver regeneration, the PM of l...
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Open AccessEnrichment and proteomic analysis of plasma membrane from rat dorsal root ganglions
Dorsal root ganglion (DRG) neurons are primary sensory neurons that conduct neuronal impulses related to pain, touch and temperature senses. Plasma membrane (PM) of DRG cells plays important roles in their fun...
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Open AccessRapid detection and curation of conserved DNA via enhanced-BLAT and EvoPrinterHD analysis
Multi-genome comparative analysis has yielded important insights into the molecular details of gene regulation. We have developed EvoPrinter, a web-accessed genomics tool that provides a single uninterrupted view...
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Article
A study on the relationship between vegetation pattern and environment in the upstream of Minjiang River, China
The vegetation pattern in the upstream of Minjiang River, and its relationship with environment factors, such as landscape position (elevation, slope, aspect), precipitation and temperature and soil are analyz...
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Article
Forest landscape ecology and its applications in China
Landscape ecology is playing an increasingly important role in resources management and landuse planning in recent decades and attracting much attention from resource managers and scientists in China as well a...
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Article
Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP)
RMP was reported to regulate transcription via competing with HBx to bind the general transcription factor IIB (TFIIB) and interacting with RPB5 subunit of RNA polymerase II as a corepressor of transcription r...
