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In Vitro Analysis of the Interaction Between Human Intestinal Epithelial Cells and Macrophage-Like Cells

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  1. Article

    Open Access

    A novel T cell-redirecting anti-GPRC5D × CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models

    G-protein-coupled receptor class 5 member D (GPRC5D) is detected in malignant plasma cells in approximately 90% of patients diagnosed with multiple myeloma (MM). Here, we constructed BsAb5003, a novel humanize...

    Urara Tomita, Yoko Ishimoto, Masaki Ri, Yumi Kawase… in Scientific Reports (2024)

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  2. Article

    F-36316 A and B, novel vasoactive compounds, isolated from Incrucipulum sp. SANK 10414

    In the course of our screening program for vasoactive compounds using co-culture assay of endothelial cells and fibroblast cells, potent activity was detected in the cultured broth of Incrucipulum sp. SANK 10414....

    Yuki Hirota-Takahata, Yoko Ishimoto, Emi Kurosawa… in The Journal of Antibiotics (2017)

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  3. Article

    Vestaines, novel vasoactive compounds, isolated from Streptomyces sp. SANK 63697

    We conducted a screening program for vasoactive compounds and detected a potent activity in the cultured broth of Streptomyces sp. SANK 63697. From the cultured broth, two active compounds, vestaine A1 and B1, we...

    Yuki Hirota-Takahata, Emi Kurosawa, Yoko Ishimoto… in The Journal of Antibiotics (2017)

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