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  1. No Access

    Article

    Molecular Mechanisms and Structural Basis of Retigabine Analogues in Regulating KCNQ2 Channel

    KCNQ2 channel is one of the important members of potassium voltage-gated channel. KCNQ2 is closely related to neuronal excitatory diseases including epilepsy and neuropathic pain, and also acts as a drug targe...

    Sai Shi, Junwei Li, Fude Sun, Yafei Chen, Chunli Pang… in The Journal of Membrane Biology (2020)

  2. No Access

    Article

    Anchor Effect of Interactions Between Kinesin’s Nucleotide-Binding Pocket and Microtubule

    Microtubule not only provides the track for kinesin but also modulates kinesin’s mechanochemical cycle. Microtubule binding greatly increases the rates of two chemical steps occurring inside the nucleotide-bin...

    Yumei **, Yizhao Geng, Lina Lü, Yilong Ma… in Cellular and Molecular Bioengineering (2017)