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  1. No Access

    Article

    Ucf-101 alleviates Ischaemia/Reperfusion induced retinal inflammation and injury via suppressing oxidative damage

    The Omi/HtrA2 inhibitor 5-[5-(2-nitrophenyl) furfuryliodine]-1,3-diphenyl-2-thiobarbituric acid (Ucf-101) has shown neuroprotective effects in the central nervous system. However, whether Ucf-101 can protect r...

    Yuan-Jun Qin, Guangyi Huang, **g Liao, Li Jiang… in Journal of Molecular Histology (2024)

  2. No Access

    Article

    PPAR-γ promotes the polarization of rat retinal microglia to M2 phenotype by regulating the expression of CD200-CD200R1 under hypoxia

    Recent reports suggest that peroxisome proliferator-activated receptor-γ (PPAR-γ) could promote microglial M2 polarization to inhibit inflammation. However, the specific molecular mechanisms that trigger PPAR-...

    Yiyi Hong, Li Jiang, Fen Tang, Mingyuan Zhang, Ling Cui… in Molecular Biology Reports (2023)

  3. No Access

    Article

    An artificial intelligence approach to classify pathogenic fungal genera of fungal keratitis using corneal confocal microscopy images

    Fungal keratitis is a common cause of blindness worldwide. Timely identification of the causative fungal genera is essential for clinical management. In vivo confocal microscopy (IVCM) provides useful informat...

    Ningning Tang, Guangyi Huang, Daizai Lei, Li Jiang, Qi Chen… in International Ophthalmology (2023)

  4. No Access

    Article

    Cavin-1 promotes M2 macrophages/microglia polarization via SOCS3

    Our study aimed to investigate the function of Cavin-1 and SOCS3 in macrophages/microglia M2 polarization and further explored the relevant mechanism.

    Wei Huang, Yiyi Hong, Wen**g He, Li Jiang, Wen Deng, Biyan Peng… in Inflammation Research (2022)