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  1. No Access

    Article

    Ketamine relieves depression-like behaviors induced by chronic postsurgical pain in rats through anti-inflammatory, anti-oxidant effects and regulating BDNF expression

    Clinically, chronic postsurgical pain (CPSP) is very common. Many CPSP patients may experience depression. Thus far, little is known about the mechanism of the comorbidity of CPSP and depression. Ketamine has ...

    Yitian Yang, Yuxiang Song, Xuan Zhang, Weixing Zhao, Tao Ma, Yi Liu… in Psychopharmacology (2020)

  2. Article

    Open Access

    Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice

    It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolys...

    Weixing Zhao, Zhipeng Xu, Jiangbei Cao, Qiang Fu… in Journal of Neuroinflammation (2019)

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