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Article
Fast reconstruction of water-tight surface mesh of neurons
Neuron morphology reconstruction from high-resolution imaging data is essential for understanding the structure and function of the brain in neuroscience. However, previous methods cannot achieve both water-ti...
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Article
Open AccessGlobally distributed Myxococcota with photosynthesis gene clusters illuminate the origin and evolution of a potentially chimeric lifestyle
Photosynthesis is a fundamental biogeochemical process, thought to be restricted to a few bacterial and eukaryotic phyla. However, understanding the origin and evolution of phototrophic organisms can be impede...
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Article
Open AccessA systematic analysis of marine lysogens and proviruses
Viruses are ubiquitous in the oceans, exhibiting high abundance and diversity. Here, we systematically analyze existing genomic sequences of marine prokaryotes to compile a Marine Prokaryotic Genome Dataset (M...
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Article
Open AccessIdentification of a deep-branching thermophilic clade sheds light on early bacterial evolution
It has been proposed that early bacteria, or even the last universal common ancestor of all cells, were thermophilic. However, research on the origin and evolution of thermophily is hampered by the difficultie...
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Article
Open AccessAnaerobic degradation of organic carbon supports uncultured microbial populations in estuarine sediments
A large proportion of prokaryotic microbes in marine sediments remains uncultured, hindering our understanding of their ecological functions and metabolic features. Recent environmental metagenomic studies sug...
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Article
Open AccessProteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria
Ancestral metabolism has remained controversial due to a lack of evidence beyond sequence-based reconstructions. Although prebiotic chemists have provided hints that metabolism might originate from non-enzymat...
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Article
Rad54L promotes bladder cancer progression by regulating cell cycle and cell senescence
Bladder cancer (BCa) is the most prevalent cancer of the urinary system, but its pathogenesis is still poorly understood. Several reports have suggested that gene damage repair is highly correlated with tumor ...
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Article
Expanding Asgard members in the domain of Archaea sheds new light on the origin of eukaryotes
The hypothesis that eukaryotes originated from within the domain Archaea has been strongly supported by recent phylogenomic analyses placing Heimdallarchaeota-Wukongarchaeota branch from the Asgard superphylum...
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Article
Open AccessThe origin and impeded dissemination of the DNA phosphorothioation system in prokaryotes
Phosphorothioate (PT) modification by the dnd gene cluster is the first identified DNA backbone modification and constitute an epigenetic system with multiple functions, including antioxidant ability, restriction...
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Article
New approaches for archaeal genome-guided cultivation
Archaea, one of the three domains of life along with Bacteria and Eukarya, contains ancient life forms such as methanogen that are observed today on Earth, and one lineage Asgard archaea is also considered the...
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Article
Open AccessGenomic and enzymatic evidence of acetogenesis by anaerobic methanotrophic archaea
Anaerobic oxidation of methane (AOM) mediated by anaerobic methanotrophic archaea (ANME) is the primary process that provides energy to cold seep ecosystems by converting methane into inorganic carbon. Notably...
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Article
Open AccessMicrobial succession during the transition from active to inactive stages of deep-sea hydrothermal vent sulfide chimneys
Deep-sea hydrothermal vents are highly productive biodiversity hotspots in the deep ocean supported by chemosynthetic microorganisms. Prominent features of these systems are sulfide chimneys emanating high-tem...
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Article
Metal-dependent anaerobic methane oxidation in marine sediment: Insights from marine settings and other systems
Anaerobic oxidation of methane (AOM) plays a crucial role in controlling global methane emission. This is a microbial process that relies on the reduction of external electron acceptors such as sulfate, nitrat...
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Article
Thermal error compensation model for a motorized spindle with shaft core cooling based on exponential function
Thermal issues become more serious for high-speed and high-precision motorized spindle. Thermal error compensation is cost-effective and convenient to implement for this problem. To further improve the machini...
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Article
Open AccessGenomic evidence of the illumination response mechanism and evolutionary history of magnetotactic bacteria within the Rhodospirillaceae family
Magnetotactic bacteria (MTB) are ubiquitous in natural aquatic environments. MTB can produce intracellular magnetic particles, navigate along geomagnetic field, and respond to light. However, the potential mec...
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Article
Expanding anaerobic alkane metabolism in the domain of Archaea
Methanogenesis and anaerobic methane oxidation through methyl-coenzyme M reductase (MCR) as a key enzyme have been suggested to be basal pathways of archaea1. How widespread MCR-based alkane metabolism is among a...
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Article
Identification of a functional toxin–antitoxin system located in the genomic island PYG1 of piezophilic hyperthermophilic archaeon Pyrococcus yayanosii
Toxin–antitoxin (TA) system is bacterial or archaeal genetic module consisting of toxin and antitoxin gene that be organized as a bicistronic operon. TA system could elicit programmed cell death, which is sup...
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Article
Open AccessIntegrating niche-based process and spatial process in biogeography of magnetotactic bacteria
Microorganisms play key roles in biogeochemical and nutrient cycling in all ecosystems on Earth, yet little is known about the processes controlling their biogeographic distributions. Here we report an investi...
