83 Result(s)

Article

Author Correction: RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis

Zhentao Yang, Yan Wang, Yingying Zhang, **adi He, Chuan-Qi Zhong… in Nature Cell Biology (2024)

Article

Immunometabolism in cancer: basic mechanisms and new targeting strategy

Maturing immunometabolic research empowers immune regulation novel approaches. Progressive metabolic adaptation of tumor cells permits a thriving tumor microenvironment (TME) in which immune cells always lose ...

Ranran Su, Yingying Shao, Manru Huang, Donghui Liu, Haiyang Yu… in Cell Death Discovery (2024)

Article

Continuous immunosuppression is required for suppressing immune responses to xenografts in non-human primate brains

Continuous immunosuppression has been widely used in xenografts into non-human primate brains. However, how immune responses change after transplantation in host brains under continuous immunosuppressive admin...

Su Feng, Ting Zhang, Zhengxiao He, Wenchang Zhang, Yingying Chen… in Cell Regeneration (2024)

Article

NCAPD3 exerts tumor-promoting effects in prostatic cancer via dual impact on miR-30a-5p by STAT3-MALAT1 and MYC

Non-SMC condensin II complex subunit D3 (NCAPD3) is a subunit of the non-structural maintenance of chromosomes condensin II complex, which involves chromosome condensation and segregation during mitosis. NCAPD...

Yi Zhang, Yingying Shao, Jia Ren, Yuanyuan Fang, Bolin Yang… in Cell Death Discovery (2024)

Article

Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice

The Fscn2 (Fascin2) gene encodes an actin cross-linking protein that is involved in the formation of hair cell stereocilia and retina structure. Mutations in Fscn2 gene have been linked to hearing impairment and ...

Rongrong Liu, Wen**g Shang, Yingying Liu, Yi **e, Jun Luan… in Cell Death Discovery (2024)

Article

Author Correction: Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis

Zhaoxian Cai, **aotian Wu, Zijun Song, Shumin Sun, Yunxing Su… in Cell Discovery (2024)

Article

Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis

Given the rapidly aging population, aging-related diseases are becoming an excessive burden on the global healthcare system. Metformin has been shown to be beneficial to many age-related disorders, as well as ...

Zhaoxian Cai, **aotian Wu, Zijun Song, Shumin Sun, Yunxing Su… in Cell Discovery (2023)

Article

The functional effects of Piezo channels in mesenchymal stem cells

Mesenchymal stem cells (MSCs) are widely used in cell therapy, tissue engineering, and regenerative medicine because of their self-renewal, pluripotency, and immunomodulatory properties. The microenvironment i...

Zhilong Huang, Yingying Huang, **ner Ning, Haodi Li… in Stem Cell Research & Therapy (2023)

Article

Haspin balances the ratio of asymmetric cell division through Wnt5a and regulates cell fate decisions in mouse embryonic stem cells

Many different types of stem cells utilize asymmetric cell division (ACD) to produce two daughter cells with distinct fates. Haspin-catalyzed phosphorylation of histone H3 at Thr3 (H3T3ph) plays important role...

Yingying Gao, Bin Ma, Yifan Li, **angyu Wu, Shifeng Zhao… in Cell Death Discovery (2023)

Article

Standard: Human intestinal cancer organoids

Intestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade. Human intestinal cancer organoids are physiologically releva...

Hanqing Lin, Yalong Wang, Chunyan Cheng, Yuxin Qian, Jie Hao… in Cell Regeneration (2023)

Article

Emerging roles of ferroptosis-related miRNAs in tumor metastasis

Ferroptosis, a novel mode of cell death dependent on iron and reactive oxygen species, has been extensively explored during malignant tumors metastasis. Ferroptosis can interact with multiple components of the...

Zhongyi Jiang, **g Zhou, Junqi Deng, Luohong Li, Ruifeng Wang… in Cell Death Discovery (2023)

Article

A neonatal rat model of pulmonary vein stenosis

Pulmonary vein stenosis (PVS), one of the most challenging clinical problems in congenital heart disease, leads to secondary pulmonary arterial hypertension (PAH) and right ventricular (RV) hypertrophy. Due to...

Debao Li, Lisheng Qiu, Haifa Hong, Hao Chen, Peibin Zhao… in Cell & Bioscience (2023)

Article

Standard: Human intestinal organoids

Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prom...

Yalong Wang, Hanqing Lin, Lianzheng Zhao, Fan Hong, Jie Hao… in Cell Regeneration (2023)

Article

TMT-based quantitative proteomic analysis of spheroid cells of endometrial cancer possessing cancer stem cell properties

Cancer stem cells (CSCs) play an important role in endometrial cancer progression and it is potential to isolate CSCs from spheroid cells. Further understanding of spheroid cells at protein level would help fi...

Mingzhu Cao, Zhi Liu, Danming You, Yingying Pan… in Stem Cell Research & Therapy (2023)

Article

Aminoprocalcitonin protects against hippocampal neuronal death via preserving oxidative phosphorylation in refractory status epilepticus

Refractory status epilepticus (RSE) is a neurological emergency where sustaining seizure causes severe neuronal death. Currently, there is no available neuroprotectant effective in RSE. Aminoprocalcitonin (NPC...

Changgeng Song, **g**g Zhao, Jianmin Hao, Dan Mi, Jiajia Zhang… in Cell Death Discovery (2023)

Article

Correction to: NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress

Yi Wang, Yuxin Zan, Yingying Huang, **aoyun Peng, Shinan Ma, Ji Ren… in Cell Death Discovery (2023)

Article

JMJD1C promotes smooth muscle cell proliferation by activating glycolysis in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a chronic disorder characterized by hyperproliferation of pulmonary arterial smooth muscle cells (PASMCs). JMJD1C, a member of the Jumonji domain containing C (JMJC) hi...

Chen Zhang, Yue Sun, Yingying Guo, **g**g Xu, Haiyan Zhao in Cell Death Discovery (2023)

Article

Correction to: LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury

Peixing Wan, Wenru Su, Yingying Zhang, Zhidong Li… in Cell Death & Differentiation (2023)

Article

NSUN2 alleviates doxorubicin-induced myocardial injury through Nrf2-mediated antioxidant stress

Doxorubicin (DOX) is a commonly used antitumor drug, but its application has been limited because of its strong cardiac damage. This study aims to explore the role of NSUN2 in DOX-induced heart injury. C57BL/6...

Yi Wang, Yuxin Zan, Yingying Huang, **aoyun Peng, Shinan Ma, Ji Ren… in Cell Death Discovery (2023)

Article

The therapeutic prospects and challenges of human neural stem cells for the treatment of Alzheimer's Disease

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder associated with aging. Due to its insidious onset, protracted progression, and unclear pathogenesis, it is considered one of the most obs...

Chunmei Yue, Su Feng, Yingying Chen, Naihe **g in Cell Regeneration (2022)