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  1. Article

    Open Access

    Differential regulation of H3K9/H3K14 acetylation by small molecules drives neuron-fate-induction of glioma cell

    Differentiation therapy using small molecules is a promising strategy for improving the prognosis of glioblastoma (GBM). Histone acetylation plays an important role in cell fate determination. Nevertheless, wh...

    **ncheng Liu, Cui Guo, Tiandong Leng, Zhen Fan, Jialuo Mai… in Cell Death & Disease (2023)

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  2. Article

    Open Access

    Disruption of β-catenin-mediated negative feedback reinforces cAMP-induced neuronal differentiation in glioma stem cells

    Accumulating evidence supports the existence of glioma stem cells (GSCs) and their critical role in the resistance to conventional treatments for glioblastoma multiforme (GBM). Differentiation therapy represen...

    Zhijie Chen, Yingqian Zhong, Jiehong Chen, Shuxin Sun, Wenfeng Liu… in Cell Death & Disease (2022)

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