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Article
Open AccessCost-effectiveness of CYP2C19 genoty** to guide antiplatelet therapy for acute minor stroke and high-risk transient ischemic attack
Dual antiplatelet therapy (DAPT) with clopidogrel plus aspirin within 48 h of acute minor strokes and transient ischemic attacks (TIAs) has been indicated to effectively reduce the rate of recurrent strokes. H...
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Article
Ultralight and compressible mussel-inspired dopamine-conjugated poly(aspartic acid)/Fe3+-multifunctionalized graphene aerogel
The reduced graphene oxide (rGO) aerogels are particularly attractive owing to their ultralight-weight, high surface area and interconnected macroporosity for energy storage applications. However, pure rGO aer...
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Article
Population pharmacokinetics of theophylline in adult Chinese patients with asthma and chronic obstructive pulmonary disease
Background Theophylline has a narrow therapeutic range and large interindividual variability in blood levels, so a thorough understanding of its pharmacokinetic characteristics is essential. Population pharmacoki...
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Article
Open AccessEvaluation of reference genes for gene expression studies in mouse and N2a cell ischemic stroke models using quantitative real-time PCR
Real-time reverse transcription quantitative polymerase chain reaction (RT-qPCR) is a critical tool for evaluating the levels of mRNA transcribed from genes. Reliable RT-qPCR results largely depend on normaliz...