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  1. Article

    Open Access

    Histone deacetylase 1 induced by neddylation inhibition contributes to drug resistance in acute myelogenous leukemia

    This study aimed to investigate the function and mechanism of neddylation of HDAC1 underlying drug resistance of AML cells.

    Qiu-yu Lai, Ying-zhi He, **ong-wen Peng, Xuan Zhou in Cell Communication and Signaling (2019)

  2. Article

    Open Access

    IL-2Rα up-regulation is mediated by latent membrane protein 1 and promotes lymphomagenesis and chemotherapy resistance in natural killer/T-cell lymphoma

    Natural killer/T-cell lymphoma (NKTCL) is a highly aggressive non-Hodgkin lymphoma often resistant to chemotherapy. Serum level of soluble IL-2 receptor α (IL-2Rα) is elevated in NKTCL patients and correlates ...

    Liang Wang, **-wen Bi, Yu-jia Zhu, Ying-zhi He, Qiu-yu Lai in Cancer Communications (2018)