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Article
Low pretreatment serum globulin may predict favorable prognosis for gastric cancer patients
An elevated serum albumin (ALB) and albumin/globulin ratio (AGR) have been reported to be associated with a favorable prognosis for several types of cancer. However, little is known about prognostic significan...
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Article
Molecular mechanisms of secondary imatinib resistance in patients with gastrointestinal stromal tumors
Most gastrointestinal stromal tumor (GIST) patients respond to KIT inhibition therapy of imatinib, but eventually become resistant with a median time to progression of 2 years. The mechanism of acquired resist...
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Article
FHIT gene alterations in esophageal cancer and ulcerative colitis (UC)
FHIT (fragile histidine triad gene), a candidate tumor suppressor gene, was recently identified and cloned at chromosome 3p14.2. Alterations of this gene have been reported in a number of primary human tumors,...
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Article
Apparent protection from instability of repeat sequences in cancer-related genes in replication error positive gastrointestinal cancers
Genomic instability at simple repeated sequences has been observed in various types of human cancers and is considered an important mechanism in tumorigenesis. Alterations at microsatellite loci have been repo...
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Article
Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours
