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12,623 Result(s)
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Article
Metal recovery from industrial solid waste by ultrasonic-assisted hydrometallurgical leaching: a review
In the context of the circular economy, there is a need for advanced methods to recover metals from industrial waste, yet classical hydrometallurgical techniques are limited. Here, we review ultrasonic-assiste...
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Article
Open AccessAre children with IgA nephropathy different from adult patients?
Previously, several studies have indicated that pediatric IgA nephropathy (IgAN) might be different from adult IgAN, and treatment strategies might be also different between pediatric IgAN and adult IgAN.
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Comprehensive Insights into the Health Effects of Selenium Exposure and Supplementation Among the Chinese Community Middle-Aged and Elderly: a Combined Retrospective Cohort Study and Intervention Study
Selenium (Se) is an essential trace element for maintaining human health, for example, plays a crucial role in preventing aging-related diseases. However, most studies on the health effects of Se among the com...
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Calcitriol Inhibits NaAsO2 Triggered Hepatic Stellate Cells Activation and Extracellular Matrix Oversecretion by Activating Nrf2 Signaling Pathway Through Vitamin D Receptor
Previous studies, including our own, have demonstrated that arsenic exposure can induce liver fibrosis, while the underlying mechanism remains unclear and there is currently no effective pharmacological interv...
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Mind-bridge: reconstructing visual images based on diffusion model from human brain activity
Human brain vision is mysterious and complex, and it interprets the world through the connection between the brain and the eyes. In recent years, several methods have relied on fMRI to successfully reconstruct...
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Machine learning-based prediction of the outcomes of cochlear implantation in patients with inner ear malformation
The objectives of this study are twofold: first, to visualize the structure of malformed cochleae through image reconstruction; and second, to develop a predictive model for postoperative outcomes of cochlear ...
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Article
Amphidiploid production of a distant hybrid Populus simonii × P. euphratica cv. ‘**aohuyang-1’ and resulting in phenotypic variation
Populus simonii × P. euphratica cv. ‘**aohuyang-1’ is an elite variety produced by distant hybridization between Populus section Tacamahaca and sect. Turanga. However, its highly gametic sterility makes it diffic...
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Open AccessSystem-level time computation and representation in the suprachiasmatic nucleus revealed by large-scale calcium imaging and machine learning
The suprachiasmatic nucleus (SCN) is the mammalian central circadian pacemaker with heterogeneous neurons acting in concert while each neuron harbors a self-sustained molecular clockwork. Nevertheless, how sys...
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Well-dispersed Sb particles embedded on N-doped carbon nanofibers toward high-performance Li-ion battery
The alloy-type material Sb is widely used in the anode materials of lithium-ion batteries (LIBs) due to its high theoretical specific capacity. However, its serious volume expansion problem during alloying/dea...
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Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial
Percutaneous endoscopic transforaminal discectomy (PETD) is an effective method for treating lumbar disc herniation, and is typically performed under local anesthesia. However, inadequate analgesia during the ...
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Article
A novel tryptanthrin-based “on–off-on” probe for sequential sensing Cu2+/S2− in water samples
Copper ions (Cu2+) and sulfide (S2−) play essential roles in many physiologies and pathologic processes. Herein, a new “on–off-on” tryptanthrin-based probe TR-1 (TR-1) has been designed and synthesized in a facil...
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Article
Design and simulation of ultra-sensitivity reflective SRI sensor based on TLPFG
An ultra-sensitivity reflective surrounding refractive index (SRI) sensor structure based on tilted long-period fiber grating (TLPFG) is proposed in this paper. The sensitivity of the structure to SRI is great...
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Article
Small-molecule caspase-1 inhibitor CZL80 terminates refractory status epilepticus via inhibition of glutamatergic transmission
Status epilepticus (SE), a serious and often life-threatening medical emergency, is characterized by abnormally prolonged seizures. It is not effectively managed by present first-line anti-seizure medications ...
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PCB defect detection based on PSO-optimized threshold segmentation and SURF features
This paper proposes an automated inspection approach for printed circuit boards (PCBs) that can accurately locate defects to solve the issues of low precision, complex equipment, and high cost. Digital image p...
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Article
Efficacy and safety of a combination treatment of immune checkpoint inhibitors in metastatic breast cancer: a systematic review and meta-analysis
Immune checkpoint inhibitors (ICIs) in combination with chemotherapy have showed its benefits in clinical studies, and here we conducted a further evaluation on the safety and efficacy of this treatment strategy.
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Plant regeneration in the new era: from molecular mechanisms to biotechnology applications
Plants or tissues can be regenerated through various pathways. Like animal regeneration, cell totipotency and pluripotency are the molecular basis of plant regeneration. Detailed systematic studies on Arabidopsis...
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The influence of gender-specific factors influencing severe anxiety in psychotic major depression: role of thyroid hormones and depression severity
Psychotic major depression (PMD) is characterized by major depressive disorder (MDD) accompanied by delusions or hallucinations. While the prevalence of PMD and its association with anxiety have been studied, ...
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Open AccessThe Safety of Ixekizumab in Chinese Adults with Moderate-to-Severe Plaque Psoriasis: Analyses from a Prospective, Single-Arm, Multicenter, 12-Week Observational Study
Ixekizumab, a monoclonal antibody against interleukin-17A, is efficacious and well tolerated for the treatment of moderate-to-severe plaque psoriasis. However, there are limited data on the real-world safety o...
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Design and simulation of a coated 3-stage cascaded structure of CRLPG sensor for simultaneous monitoring of CTD in ocean
Based on the demand for monitoring CTD (conductivity, temperature, and depth) in the ocean, a coated 3-stage cascaded structure of cladding-reduced long-period fiber grating (CRLPG) is proposed, which could me...
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Fast and sensitive CRISPR detection by minimized interference of target amplification
Despite the great potential of CRISPR-based detection, it has not been competitive with other market diagnostics for on-site and in-home testing. Here we dissect the rate-limiting factors that undermine the pe...