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  1. Article

    Open Access

    Spatial distribution pattern of immune cells is associated with patient prognosis in colorectal cancer

    The spatial context of tumor-infiltrating immune cells (TIICs) is important in predicting colorectal cancer (CRC) patients’ clinical outcomes. However, the prognostic value of the TIIC spatial distribution is ...

    Rongfang Shen, Ying Huang, Deyang Kong, Wenhui Ma in Journal of Translational Medicine (2024)

  2. Article

    Open Access

    Redox proteomics of PANC-1 cells reveals the significance of HIF-1 signaling protein oxidation in pancreatic ductal adenocarcinoma pathogenesis

    Protein cysteine oxidation is substantially involved in various biological and pathogenic processes, but its implications in pancreatic cancer development remains poorly understood.

    Chaochao Tan, Lichun Chen, **aoyu Guan, Wenyi Huang in Journal of Translational Medicine (2024)

  3. Article

    Open Access

    Neutrophil CD64 index as a new early predictive biomarker for infected pancreatic necrosis in acute pancreatitis

    Infectious pancreatic necrosis (IPN) is a serious complication of acute pancreatitis, and early recognition and timely intervention are the keys to improving clinical outcomes. The purpose of this study was to...

    ** Huang, Ling Wu, Qianhui Ouyang, Ying Huang in Journal of Translational Medicine (2024)

  4. Article

    Open Access

    Correction: iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma

    Yanbing Dong, Ying Huang, Zhe Zhang, Aoxing Chen in Journal of Translational Medicine (2023)

  5. Article

    Open Access

    The oncogenic role of NF1 in gallbladder cancer through regulation of YAP1 stability by direct interaction with YAP1

    Gallbladder cancer (GBC) is the most prevalent and invasive biliary tract malignancy. As a GTPase-activating protein, Neurofibromin 1 (NF1) is a tumor suppressor that negatively regulates the RAS signaling pat...

    Lingxiao Zhang, Lin Jiang, Ling Zeng, Zhaohui ** in Journal of Translational Medicine (2023)

  6. Article

    Open Access

    iRGD-modified memory-like NK cells exhibit potent responses to hepatocellular carcinoma

    Cytokine-induced memory-like natural killer (CIML NK) cells have been found to possess potent antitumor responses and induce complete remissions in patients with leukemia. However, the poor infiltration of tra...

    Yanbing Dong, Ying Huang, Zhe Zhang, Aoxing Chen in Journal of Translational Medicine (2023)

  7. Article

    Open Access

    Risk stratification of lateral neck recurrence for patients with pN1a papillary thyroid cancer

    Lateral neck is not recommended for dissection in patients with pN1a papillary thyroid cancer (PTC), but its recurrence risk has not been well stratified. We aimed to develop a risk stratification system for l...

    Siyuan Xu, Hui Huang, Ying Huang, **aolei Wang, Zhengang Xu, Shaoyan Liu in BMC Cancer (2022)

  8. Article

    Open Access

    Tissue mechanics and expression of TROP2 in oral squamous cell carcinoma with varying differentiation

    Trophoblast cell surface antigen 2 (TROP2) is overexpressed in many squamous cell carcinomas and promotes tumor development and invasion. The association between TROP2 expression and occurrence and development...

    Bao** Zhang, Shuting Gao, Rui** Li, Yiting Li, Rui Cao, **gyang Cheng in BMC Cancer (2020)

  9. Article

    Open Access

    Downregulated SPINK4 is associated with poor survival in colorectal cancer

    SPINK4 is known as a gastrointestinal peptide in the gastrointestinal tract and is abundantly expressed in human goblet cells. The clinical significance of SPINK4 in colorectal cancer (CRC) is largely unknown.

    **aojie Wang, Qian Yu, Waleed M. Ghareeb, Yiyi Zhang, **ngrong Lu, Ying Huang in BMC Cancer (2019)

  10. Article

    Open Access

    Evaluation of transabdominal ultrasound after oral administration of an echoic cellulose-based gastric ultrasound contrast agent for gastric cancer

    With the remarkable improvements in ultrasound equipment, transabdominal ultrasound after oral administration of an echoic cellulose-based gastric ultrasound contrast agent (TUS-OCCA) has recently been suggest...

    Zhijun Liu, **tao Guo, Shupeng Wang, Ying Zhao, **g Li, Weidong Ren in BMC Cancer (2015)

  11. Article

    Open Access

    Exploring the interaction between SNP genotype and postmenopausal hormone therapy effects on stroke risk

    Genome-wide association studies have identified several genomic regions that are associated with stroke risk, but these provide an explanation for only a small fraction of familial stroke aggregation. Genotype...

    Ying Huang, Dennis G Ballinger, Renee Stokowski, Erica Beilharz in Genome Medicine (2012)

  12. Article

    Open Access

    Inhibitory effect of Bifidobacterium infantis-mediated sKDR prokaryotic expression system on angiogenesis and growth of Lewis lung cancer in mice

    To construct the Bifidobacterium infantis-mediated soluble kinase insert domain receptor (sKDR) prokaryotic expression system and to observe its inhibitory effect on growth of human umbilicus vessel endothelial c...

    Zhao-Jun Li, Hong Zhu, Bu-Yun Ma, Fen Zhao, Shu-Hua Mao, Tai-Guo Liu in BMC Cancer (2012)

  13. Article

    Open Access

    Erratum To: Genetic variants in the MRPS30region and postmenopausal breast cancer risk

    Ying Huang, Dennis G Ballinger, James Y Dai, Ulrike Peters in Genome Medicine (2012)

  14. No Access

    Chapter

    Evidence-based Materia Medica for Cancer Chemoprevention

    Cancer is the second leading cause of death in the world, and current therapeutic outcomes are still not satisfactory. Cancer chemoprevention is an important strategy to reduce cancer morbidity by using non- o...

    Sunil Prabhu, Ying Huang, Jeffrey Wang in Materia Medica for Various Cancers (2012)

  15. Article

    Open Access

    Genetic variants in the MRPS30 region and postmenopausal breast cancer risk

    Genome-wide association studies have identified several genomic regions that are associated with breast cancer risk, but these provide an explanation for only a small fraction of familial breast cancer aggrega...

    Ying Huang, Dennis G Ballinger, James Y Dai, Ulrike Peters in Genome Medicine (2011)

  16. Article

    Open Access

    Inhibitory effect of ginsenoside Rg3 combined with gemcitabine on angiogenesis and growth of lung cancer in mice

    Ginsenoside Rg3, a saponin extracted from ginseng, inhibits angiogenesis. The combination of low-dose chemotherapy and anti-angiogenic inhibitors suppresses growth of experimental tumors more effectively than ...

    Tai-Guo Liu, Ying Huang, Dan-Dan Cui, **ao-Bing Huang, Shu-Hua Mao in BMC Cancer (2009)