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3,915 Result(s)
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Article
Associations of Rheumatoid Factor, Rheumatoid Arthritis, and Interleukin-6 Inhibitor with the Prognosis of Ischemic Stroke: a Prospective Multicenter Cohort Study and Mendelian Randomization Analysis
Rheumatoid factor (RF), an established diagnostic biomarker for rheumatoid arthritis (RA), is associated with cardiovascular diseases, but its impact on clinical outcomes of ischemic stroke remains unclear. We...
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Article
Multi-task scheduling in vehicular edge computing: a multi-agent reinforcement learning approach
Vehicular Edge Computing (VEC) represents a computational paradigm designed to optimize vehicular performance and enhance vehicle services. It entails strategically deploying computational and storage resource...
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Characteristics of Neonatal Sepsis and Predictive Values of Polyfunctional Assessment of Umbilical Cord Neutrophils Based on Single Cell Proteomic Secretion
The early diagnosis of neonatal sepsis is crucial as it remains a prevalent cause of neonatal mortality. In this study, we conducted an analysis on the clinical data and detection indicators of 22 cases with s...
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Open AccessmiR-455/GREM1 axis promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing M2 macrophage polarization
Colorectal cancer is among the most common malignant tumors affecting the gastrointestinal tract. Liver metastases, a complication present in approximately 50% of colorectal cancer patients, are a considerable...
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Open AccessA retrospective study on the impact of radiotherapy on the survival outcomes of small cell lung cancer patients based on the SEER database
Small cell lung cancer (SCLC) patients exhibit significant heterogeneity in tumor burden, physical condition, and responses to initial treatment. This diversity in treatment responses can result in varying tre...
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Article
Open AccessStrain-induced activation of chiral-phonon emission in monolayer WS2
We report a theoretical investigation of the ultrafast dynamics of electrons and phonons in strained monolayer WS2 following photoexcitation. We show that strain substantially modifies the phase space for electro...
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Effect of Temperature and Grain Boundary on Void Evolution in Irradiated Copper: A Phase-Field Study
The continued existence of high-energy radiation in nuclear reactors at high temperatures results in the formation of radiation-induced voids, which will further lead to inevitable swellings of polycrystalline...
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Open AccessExperimental study on the mechanical characteristics of weakly cemented mudstone under different loading rates
With the gradual shift of coal mining to the western coal mining region of China, floor heave in weakly cemented mudstone roadways has become an issue affecting the safety and efficiency of coal mine productio...
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Article
On weak convergence of quantile-based empirical likelihood process for ROC curves
The empirical likelihood (EL) method possesses desirable qualities such as automatically determining confidence regions and circumventing the need for variance estimation. As an extension, a quantile-based EL ...
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Article
TGF-β/SMAD Pathway Mediates Cadmium Poisoning-Induced Chicken Liver Fibrosis and Epithelial-Mesenchymal Transition
Cadmium(Cd) is a toxic heavy metal widely present in the environment, capable of accumulating in the liver and causing liver damage. In this study, the mechanism of cadmium-induced liver fibrosis in chickens w...
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Targeting pericentric non-consecutive motifs for heterochromatin initiation
Pericentric heterochromatin is a critical component of chromosomes marked by histone H3 K9 (H3K9) methylation1–3. However, what recruits H3K9-specific histone methyltransferases to pericentric regions in vertebra...
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Article
Open AccessMacrophage migration inhibitory factor (MIF) suppresses mitophagy through disturbing the protein interaction of PINK1-Parkin in sepsis-associated acute kidney injury
Damage to renal tubular epithelial cells (RTECs) signaled the onset and progression of sepsis-associated acute kidney injury (SA-AKI). Recent research on mitochondria has revealed that mitophagy plays a crucia...
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Research progress of propofol in alleviating cerebral ischemia/reperfusion injury
Ischemic stroke is a leading cause of adult disability and death worldwide. The primary treatment for cerebral ischemia patients is to restore blood supply to the ischemic region as quickly as possible. Howeve...
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Open AccessThe circadian gene ARNTL2 promotes nasopharyngeal carcinoma invasiveness and metastasis through suppressing AMOTL2-LATS-YAP pathway
Metastasis is the major culprit of treatment failure in nasopharyngeal carcinoma (NPC). Aryl hydrocarbon receptor nuclear translocator like 2 (ARNTL2), a core circadian gene, plays a crucial role in the develo...
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Examining Chinese preservice mathematics teachers’ adoption of AI chatbots for learning: Unpacking perspectives through the UTAUT2 model
Integrating AI Chatbots into teaching and learning activities is a growing trend, and understanding the readiness of preservice mathematics teachers to use AI Chatbots is crucial for successful implementation ...
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Article
COVID-19 in patients with myasthenia gravis: a single-center retrospective study in China
Coronavirus disease 2019 (COVID-19) has been a great concern since 2019. Patients with myasthenia gravis (MG) may be at higher risk of COVID-19 and a more severe disease course. We examined the associations be...
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Article
Lower Bound on Translative Covering Density of Tetrahedra
In this paper, we present the first nontrivial lower bound on the translative covering density of tetrahedra. To this end, we show the lower bound, in any translative covering of tetrahedra, on the density rel...
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Article
Comparison of Sleeve Gastrectomy with Loop Duodenojejunal Bypass Versus One Anastomosis Gastric Bypass for Type 2 Diabetes: The Role of Pylorus Preservation
One anastomosis gastric bypass (OAGB) is recognized as a standard procedure in metabolic surgery. However, concerns about postoperative bile reflux and nutritional risks are prevalent. Comparatively, sleeve ga...
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Association of Crohn’s disease and ulcerative colitis with the risk of neurological diseases: a large-scale Mendelian randomization study
Observational studies suggested increased risks of Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS) in patients with Crohn’s disease (CD) and ulcerative colitis (UC). We aimed to...
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High-performance wearable bimetallic nanowire-assisted composite foams for efficient electromagnetic interference shielding, infrared stealth, and piezoresistive sensing
With the accelerated development of modern detection and communication technology, the multifunctional wearable materials with excellent electromagnetic interference (EMI) shielding, infrared stealth, and huma...