Skip to main content

5 Result(s)

within Yim Ling Mak Remove this filter

and

  1. No Access

    Article

    Pacific Ciguatoxin Induces Excitotoxicity and Neurodegeneration in the Motor Cortex Via Caspase 3 Activation: Implication for Irreversible Motor Deficit

    Consumption of fish containing ciguatera toxins or ciguatoxins (CTXs) causes ciguatera fish poisoning (CFP). In some patients, CFP recurrence occurs even years after exposure related to CTXs accumulation. Paci...

    Pallavi Asthana, Ni Zhang, Gajendra Kumar… in Molecular Neurobiology (2018)

  2. No Access

    Article

    Acute Exposure to Pacific Ciguatoxin Reduces Electroencephalogram Activity and Disrupts Neurotransmitter Metabolic Pathways in Motor Cortex

    Ciguatera fish poisoning (CFP) is a common human food poisoning caused by consumption of ciguatoxin (CTX)-contaminated fish affecting over 50,000 people worldwide each year. CTXs are classified depending on th...

    Gajendra Kumar, Ngan Pan Bennett Au, Elva Ngai Yu Lei… in Molecular Neurobiology (2017)

  3. Article

    Open Access

    Ciguatoxin reduces regenerative capacity of axotomized peripheral neurons and delays functional recovery in pre-exposed mice after peripheral nerve injury

    Ciguatera fish poisoning (CFP) results from consumption of tropical reef fish containing ciguatoxins (CTXs). Pacific (P)-CTX-1 is among the most potent known CTXs and the predominant source of CFP in the endem...

    Ngan Pan Bennett Au, Gajendra Kumar, Pallavi Asthana, Chung Tin… in Scientific Reports (2016)

    Download PDF (4365 KB) View Article

  4. No Access

    Article

    Simultaneous quantification of Pacific ciguatoxins in fish blood using liquid chromatography–tandem mass spectrometry

    Ciguatera fish poisoning (CFP) is a food intoxication caused by exposure to ciguatoxins (CTXs) in coral reef fish. Rapid analytical methods have been developed recently to quantify Pacific-CTX-1 (P-CTX-1) in f...

    Yim Ling Mak, Jia Jun Wu, Wing Hei Chan… in Analytical and Bioanalytical Chemistry (2013)

  5. No Access

    Article

    Validation of an accelerated solvent extraction liquid chromatography–tandem mass spectrometry method for Pacific ciguatoxin-1 in fish flesh and comparison with the mouse neuroblastoma assay

    Ciguatera fish poisoning (CFP) is a global foodborne illness caused by consumption of seafood containing ciguatoxins (CTXs) originating from dinoflagellates such as Gambierdiscus toxicus. P-CTX-1 has been suggest...

    Jia Jun Wu, Yim Ling Mak, Margaret B. Murphy… in Analytical and Bioanalytical Chemistry (2011)