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Article
An epigenome-wide association study of waist circumference in Chinese monozygotic twins
Central obesity poses significant health risks because it increases susceptibility to multiple chronic diseases. Epigenetic features such as DNA methylation may be associated with specific obesity traits, whic...
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Article
Integrated genetic and epigenetic analyses uncovered GLP1R association with metabolically healthy obesity
Both genetic and epigenetic variations of GLP1R influence the development and progression of obesity. However, the underlying mechanism remains elusive. This study aims to explore the mediation roles of obesity-r...
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Article
DNA methylome profiling in identical twin pairs discordant for body mass index
Body mass index (BMI) serves as an important measurement of obesity and adiposity, which are highly correlated with cardiometabolic diseases. Although high heritability has been estimated, the identified genet...