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    Article

    Albumycin, a new isoindolequinone from Streptomyces albus J1074 harboring the fluostatin biosynthetic gene cluster

    Heterologous expression of the fluostatin biosynthetic gene cluster from the marine-derived Micromonospora rosaria SCSIO N160 in Streptomyces albus J1074 led to the isolation of a novel isoindolequinone albumycin...

    Chunshuai Huang, Chunfang Yang, Wenjun Zhang, Yiguang Zhu in The Journal of Antibiotics (2019)

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    Article

    Identification and characterization of a biosynthetic gene cluster for tryptophan dimers in deep sea-derived Streptomyces sp. SCSIO 03032

    Tryptophan dimers (TDs) are an important class of natural products with diverse bioactivities and share conserved biosynthetic pathways. We report the identification of a partial gene cluster (spm) responsible fo...

    Liang Ma, Wenjun Zhang, Yiguang Zhu in Applied Microbiology and Biotechnology (2017)

  3. Article

    Open Access

    Mob/oriT, a mobilizable site-specific recombination system for unmarked genetic manipulation in Bacillus thuringiensis and Bacillus cereus

    Bacillus thuringiensis and Bacillus cereus are two important species in B. cereus group. The intensive study of these strains at the molecular level and construction of genetically mod...

    Pengxia Wang, Yiguang Zhu, Yuyang Zhang, Chunyi Zhang in Microbial Cell Factories (2016)

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    Article

    Characterization of the sugar-O-methyltransferase LobS1 in lobophorin biosynthesis

    Lobophorins A (1) and B (2) belong to a large group of spirotetronate natural products with potent antibacterial and antitumor activities. The cloning of the lobophorin biosynthesis gene cluster from the deep-sea...

    Ji **ao, Qingbo Zhang, Yiguang Zhu, Sumei Li in Applied Microbiology and Biotechnology (2013)

  5. Article

    New diketopiperazine derivatives from a deep-sea-derived Nocardiopsis alba SCSIO 03039

    The strain SCSIO 03039 was isolated from a sediment sample in the Indian Ocean and was characterized as a Nocardiopsis alba species on the basis of its 16S rRNA gene sequence. Seven diketopiperazines (DKPs), incl...

    Qingbo Zhang, Sumei Li, Yuchan Chen, **npeng Tian in The Journal of Antibiotics (2013)