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  1. Article

    Open Access

    Budding of Tiger Frog Virus (an Iridovirus) from HepG2 Cells via Three Ways Recruits the ESCRT Pathway

    The cellular endosomal sorting complex required for transport (ESCRT) pathway is a multifunctional pathway involved in cell physiological activities. While the majority of RNA viruses bearing L-domains are kno...

    Shu Mi, **ao-Wei Qin, Yi-Fan Lin, Jian He, Nan-Nan Chen, Chang Liu in Scientific Reports (2016)

  2. No Access

    Article

    Maintenance and propagation of a deleterious mitochondrial genome by the mitochondrial unfolded protein response

    In the context of mitochondrial genome heteroplasmy that causes defective oxidative phosphorylation in C. elegans, the ATFS-1-mediated mitochondrial unfolded protein response maintains the deleterious mitochondri...

    Yi-Fan Lin, Anna M. Schulz, Mark W. Pellegrino, Yun Lu, Shai Shaham in Nature (2016)

  3. Article

    Open Access

    Caveolae Restrict Tiger Frog Virus Release in HepG2 cells and Caveolae-Associated Proteins Incorporated into Virus Particles

    Caveolae are flask-shaped invaginations of the plasma membrane. Caveolae play important roles in the process of viruses entry into host cells, but the roles of caveolae at the late stage of virus infection wer...

    Jian He, Yi-Wen Zheng, Yi-Fan Lin, Shu Mi, **ao-Wei Qin in Scientific Reports (2016)

  4. No Access

    Article

    In vivo cardiac reprogramming contributes to zebrafish heart regeneration

    A cardiac injury study in zebrafish reveals the plasticity of heart cell lineages as shown by a Notch-dependent transdifferentiation of atrial to ventricular cardiomyocytes, regenerating a cell type that is da...

    Ruilin Zhang, Peidong Han, Hongbo Yang, Kunfu Ouyang, Derek Lee, Yi-Fan Lin in Nature (2013)