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  1. Article

    Open Access

    Atypical presentation of "takotsubo cardiomyopathy" without ST segment elevation: a case report

    "Takotsubo cardiomyopathy" is characterized by transient LV dysfunction and mimicking acute myocardial infarction.

    Yen-Wen Liu, Ju-Yi Chen, Wei-Chuan Tsai, Jyh-Hong Chen in Cases Journal (2008)

  2. Article

    Open Access

    Tuberculous constrictive pericarditis with concurrent active pulmonary tuberculous infection: a case report

    In some particular endemic area, it is not uncommon to see patients with tuberculosis pericarditis. However, it takes a period of time from tuberculous pericarditis to constrictive pericarditis. There is still...

    Yen-Wen Liu, Huey-Ru Tsai, Wen-Huang Li, Li-Jen Lin, Jyh-Hong Chen in Cases Journal (2009)

  3. No Access

    Article

    Increased C-reactive protein is associated with future development of diabetes mellitus in essential hypertensive patients

    Coexistence of hypertension and diabetes mellitus (DM) increases the risk of cardiovascular disease. However, factors associated with future development of DM have not been well elucidated in patients already ...

    Chiung-Mei Weng, Chang-Hua Chou, Yao-Yi Huang, Chih-Chan Lin in Heart and Vessels (2010)

  4. No Access

    Article

    Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts

    Regeneration of the heart muscle after myocardial infarction with cardiomyocytes derived from human embryonic stem cells is demonstrated in non-human primates, with the grafts showing evidence of electromechan...

    James J. H. Chong, **ulan Yang, Creighton W. Don, Elina Minami, Yen-Wen Liu in Nature (2014)

  5. No Access

    Article

    Left ventricular global longitudinal strain is independently associated with mortality in septic shock patients

    Conventional echocardiography may not detect subtle cardiac dysfunction of septic patients. Two-dimensional left ventricular (LV) global peak systolic longitudinal strain (GLS) can detect early cardiac dysfunc...

    Wei-Ting Chang, Wen-Huang Lee, Wei-Ting Lee, Po-Sheng Chen in Intensive Care Medicine (2015)

  6. No Access

    Article

    Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates

    Cardiomyocyte transplantation after heart attack improves contractile function in monkeys.

    Yen-Wen Liu, Billy Chen, **ulan Yang, James A Fugate in Nature Biotechnology (2018)

  7. Article

    Erratum: Human embryonic stem cell–derived cardiomyocytes restore function in infarcted hearts of non-human primates

    Nat. Biotechnol. 36, 597–605 (2018); published online 2 July 2018; corrected after print 18 July 2018 In the version of this article initially published, NIH grant P51 OD010425 was omitted. The error has been ...

    Yen-Wen Liu, Billy Chen, **ulan Yang, James A Fugate in Nature Biotechnology (2018)

  8. Article

    Open Access

    The biochemical and electrophysiological profiles of amniotic fluid-derived stem cells following Wnt signaling modulation cardiac differentiation

    Owing to the beneficial properties of amniotic fluid-derived stem cells (AFSCs), including pluripotency and the lack of ethical issues associated with embryonic stem cells (ESCs), they should be a promising ce...

    Yen-Wen Liu, Yi-Hsein Fang, Chi-Ting Su, Shiaw-Min Hwang in Cell Death Discovery (2019)

  9. No Access

    Article

    Uncertainties in the representative indentation stress and strain using spherical nanoindentation

    In this study, we reviewed the definitions of indentation strain and stress proposed from earlier studies and then calculated indentation strain–stress curves according to 20 combinations of five indentation s...

    Fei-Ya Huang, Yen-Wen Liu, Jui-Chao Kuo in Applied Nanoscience (2021)

  10. Article

    Open Access

    Subtle cardiac dysfunction in lymphoma patients receiving low to moderate dose chemotherapy

    Left ventricular (LV) global peak systolic longitudinal strain (GLS) is a sensitive measurement for detecting subtle LV systolic dysfunction and a powerful prognostic predictor. However, the clinical implicati...

    Hsien-Yuan Chang, Chun-Hui Lee, Po-Lan Su, Sin-Syue Li in Scientific Reports (2021)

  11. Article

    Open Access

    Tumor endothelial marker 1 is upregulated in heart after cardiac injury and participates in cardiac remodeling

    Tumor endothelial marker 1 (TEM1) is a transmembrane glycoprotein that appears on mesenchymal lineage-derived cells during embryogenesis, but its expression greatly reduces after birth. Re-upregulation of TEM1...

    Po-Sheng Chen, Wen-Han Feng, Tzu-Hsien Tsai, Yi-Kai Hong in Scientific Reports (2022)

  12. Article

    Open Access

    Application of genetic risk score for in-stent restenosis of second- and third-generation drug-eluting stents in geriatric patients

    The second-and third-generation drug-eluting stents (DESs) in-stent restenosis (ISR) genetic risk score (GRS) model has been previously validated. However, the model has not been validated in geriatric patient...

    Yu-Ling Hsu, Mu-Shiang Huang, Hsien-Yuan Chang, Cheng-Han Lee in BMC Geriatrics (2023)

  13. Article

    Open Access

    Gut butyrate-producers confer post-infarction cardiac protection

    The gut microbiome and its metabolites are increasingly implicated in several cardiovascular diseases, but their role in human myocardial infarction (MI) injury responses have yet to be established. To address...

    Hung-Chih Chen, Yen-Wen Liu, Kuan-Cheng Chang, Yen-Wen Wu in Nature Communications (2023)