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Article
Open AccessGenome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans
Phosphatases, together with kinases and transcription factors, are key components in cellular signalling networks. Here, we present a systematic functional analysis of the phosphatases in Cryptococcus neoformans,...
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Article
Open AccessDestabilization of light NREM sleep by thalamic PLCβ4 deletion impairs sleep-dependent memory consolidation
Sleep abnormality often accompanies the impairment of cognitive function. Both rapid eye movement (REM) and non-REM (NREM) sleep have associated with improved memory performance. However, the role of compositi...
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Article
Open AccessFungal kinases and transcription factors regulating brain infection in Cryptococcus neoformans
Cryptococcus neoformans causes fatal fungal meningoencephalitis. Here, we study the roles played by fungal kinases and transcription factors (TFs) in blood-brain barrier (BBB) crossing and brain infection in mice...
