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  1. No Access

    Article

    Recipient ABCB1, donor and recipient CYP3A5 genotypes influence tacrolimus pharmacokinetics in liver transplant cases

    Effective immunosuppression through optimization of trough levels tacrolimus reduces post-transplant mortality rate in liver transplant cases.

    Shaik Mohammad Naushad, Addepalli Pavani, Yedluri Rupasree… in Pharmacological Reports (2019)

  2. No Access

    Article

    Classification and regression tree-based prediction of 6-mercaptopurine-induced leucopenia grades in children with acute lymphoblastic leukemia

    The rationale of the current study was to develop 6-mercaptopurine (6-MP)-mediated hematological toxicity prediction model for acute lymphoblastic leukemia (ALL) therapeutic management.

    Shaik Mohammad Naushad, Patchava Dorababu… in Cancer Chemotherapy and Pharmacology (2019)

  3. No Access

    Article

    Application of Various Statistical Models to Explore Gene–Gene Interactions in Folate, Xenobiotic, Toll-Like Receptor and STAT4 Pathways that Modulate Susceptibility to Systemic Lupus Erythematosus

    In view of our previous studies showing an independent association of genetic polymorphisms in folate, xenobiotic, and toll-like receptor (TLR) pathways with the risk for systemic lupus erythematosus (SLE), we...

    Yedluri Rupasree, Shaik Mohammad Naushad, Ravi Varshaa… in Molecular Diagnosis & Therapy (2016)

  4. No Access

    Article

    Multifactor dimensionality reduction analysis to elucidate the cross-talk between one-carbon and xenobiotic metabolic pathways in multi-disease models

    Putatively functional polymorphisms of one-carbon and xenobiotic metabolic pathways influence susceptibility for wide spectrum of diseases. The current study was aimed to explore gene–gene interactions among ...

    Shaik Mohammad Naushad, Sana Venkata Vijayalakshmi… in Molecular Biology Reports (2015)

  5. No Access

    Article

    Cross-Talk Between One-Carbon Metabolism and Xenobiotic Metabolism: Implications on Oxidative DNA Damage and Susceptibility to Breast Cancer

    The aim of this case–control study is to explore the role of aberrations in xenobiotic metabolism in inducing oxidative DNA damage and altering the susceptibility to breast cancer. Cytochrome P4501A1 (CYP1A1) ...

    Shaik Mohammad Naushad, Cheruku Apoorva Reddy… in Cell Biochemistry and Biophysics (2011)