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Open AccessThe clinical relevance of a polygenic risk score for type 2 diabetes mellitus in the Korean population
The clinical utility of a type 2 diabetes mellitus (T2DM) polygenic risk score (PRS) in the East Asian population remains underexplored. We aimed to examine the potential prognostic value of a T2DM PRS and ass...
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Open AccessComparison of anticholinergic burden with chronic polypharmacy on functional decline and mortality in Korean older people: a retrospective nationwide cohort study
We aimed to evaluate the association of anticholinergic burden and chronic polypharmacy with the incidence of functional decline and all-cause mortality, and to determine the difference between anticholinergic...
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Article
Open AccessEffects of abdominal aortic aneurysm on long-term survival in lung cancer patients
The major causes of death in patients with abdominal aortic aneurysm (AAA) are cardiovascular disease and cancer. The purpose of this study was to evaluate the effect of AAA on long-term survival in lung cance...
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Article
Cancer risks in patients with psoriasis administered biologics therapy: a nationwide population-based study
To assess cancer risks in patients with psoriasis and the effect of TNF-α inhibitor and interleukin (IL)-12/23 inhibitor therapy on those cancer risks.
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Open AccessAuthor Correction: Association between weight loss agents and elevated liver enzymes: a population‑based cross‑sectional study
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Open AccessAuthor Correction: Risk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study
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Article
Open AccessRisk of incident autoimmune diseases in patients with newly diagnosed psoriatic disease: a nationwide population-based study
There are limited large population-based cohort studies on the risk of incident autoimmune diseases among patients with newly diagnosed psoriatic disease. The objective of this study was to assess the risk of ...
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Article
Open AccessAssociation between weight loss agents and elevated liver enzymes: a population-based cross-sectional study
The widespread use of body weight control agents might be related to liver enzyme elevation, but this potential association has only been documented in a few case reports. This study aimed to investigate the a...
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Article
Open AccessActive surveillance for adverse events of influenza vaccine safety in elderly cancer patients using self-controlled tree-temporal scan statistic analysis
Both cancer patients and the elderly are at high risk of develo** flu complications, so influenza vaccination is recommended. We aimed to evaluate potential adverse events (AEs) following influenza vaccinati...
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Article
Open AccessEpidemiology and comorbidities in idiopathic pulmonary fibrosis: a nationwide cohort study
Idiopathic pulmonary fibrosis (IPF) is frequently accompanied by comorbidities, with the management of these comorbidities crucial for clinical outcomes. This study investigated the prevalence, incidence, chan...
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Article
Open AccessAssociation of the atherogenic index of plasma with cardiovascular risk beyond the traditional risk factors: a nationwide population-based cohort study
The atherogenic index of plasma (AIP) is composed of triglycerides and high-density lipoprotein cholesterol and is a novel marker for assessing the risk of atherogenicity and cardiometabolic health. An associa...
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Open AccessExploring the impact of number and type of comorbidities on the risk of severe COPD exacerbations in Korean Population: a Nationwide Cohort Study
It is difficult to assess the impact of multiple comorbidities on clinical outcomes in chronic obstructive pulmonary disease (COPD). In this study, we aimed to investigate exacerbation-associated comorbidities...
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Open AccessEffect of multiple comorbidities on mortality in chronic obstructive pulmonary disease among Korean population: a nationwide cohort study
The effects of comorbidities on chronic obstructive pulmonary disease (COPD) have been usually studied individually in the past. In this study, we aimed to investigate the comorbidities associated with mortali...
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Article
Open AccessBody mass index trajectories and the risk for Alzheimer’s disease among older adults
The effect of body mass index (BMI) changes and variability on the risk for Alzheimer’s disease (AD) remains unclear. We analyzed 45,076 participants, whose BMI were measured on phase 1 (2002–2003), phase 2 (2...
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Article
Incidence and Outcomes of Perianal Disease in an Asian Population with Crohn’s Disease: A Nationwide Population-Based Study
Little is known about the natural history of perianal fistulas in Asian populations with Crohn’s disease (CD).
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Article
Open AccessPulmonary alveolar proteinosis in Korea: analysis of prevalence and incidence via a nationwide population-based study
Pulmonary alveolar proteinosis (PAP) is a very rare lung disease and its prevalence and incidence remain unclear. The prevalence and incidence of PAP were investigated by using nationwide claims data from the ...
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Open AccessEffect of tiotropium inhaler use on mortality in patients with tuberculous destroyed lung: based on linkage between hospital and nationwide health insurance claims data in South Korea
Although bronchodilator inhaler therapy can improve lung function in patients with tuberculous destroyed lung (TDL), its effect on mortality has not been studied. We evaluated the effect of tiotropium inhaler ...
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The association between antidepressant use and deaths from road traffic accidents: a case-crossover study
Antidepressants are some of the most commonly used psychiatric medications, but little information is available about the effects of antidepressant treatment on the risk of traffic accidents across classes of ...
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Article
Open AccessPrevalence and incidence of sarcoidosis in Korea: a nationwide population-based study
The prevalence and incidence of sarcoidosis varies worldwide. We estimated the prevalence and incidence of sarcoidosis in Korea using nationwide claims data from the Korean Health Insurance Review and Assessme...
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Prescription of Zolpidem and the Risk of Fatal Motor Vehicle Collisions: A Population-Based, Case-Crossover Study from South Korea
Zolpidem is one of the most frequently used hypnotics worldwide, but associations with serious adverse effects such as motor vehicle collisions have been reported.