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Article

A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1^G93A model of ALS

Numerous genes, including SOD1, mutated in familial and sporadic amyotrophic lateral sclerosis (f/sALS) share a role in DNA damage and repair, emphasizing genome disintegration in ALS. One possible outcome of chr...

Daniela Gerovska, Julie B. Noer, Yating Qin, Quratul Ain… in Cell & Bioscience (2023)