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Article
Presynaptic CaV2 calcium channel traffic requires CALF-1 and the α2δ subunit UNC-36
In C. elegans, the unc-2 gene encodes the pore-forming subunit of a voltage-gated Ca2+ channel (CaV2) involved in neurotransmitter release. Here, the authors identify a protein, CALF-1, that regulates the presyna...
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Article
Open AccessLeft-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans
The left and right AWC olfactory neurons in Caenorhabditis elegans differ in their functions and in their expression of chemosensory receptor genes; in each animal, one AWC randomly takes on one identity, designa...
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Article
Cdk5-dependent regulation of glucose-stimulated insulin secretion
Tight glycemic control in individuals with diabetes mellitus is essential to prevent or delay its complications1. Present treatments to reduce hyperglycemia mainly target the ATP-sensitive K+ (KATP) channel of pa...