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Article
Open AccessImprovement effects of a novel Chinese herbal formula in imiquimod and IL-23-stimulated mouse models of psoriasis
Psoriasis is a long-term inflammatory skin disease. A novel herbal formula containing nine Chinese herbal medicines, named Inflammation Skin Disease Formula (ISDF), has been prescribed in clinics for decades.
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Article
Open AccessUnderstanding the charge transfer effects of single atoms for boosting the performance of Na-S batteries
The effective flow of electrons through bulk electrodes is crucial for achieving high-performance batteries, although the poor conductivity of homocyclic sulfur molecules results in high barriers against the p...
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Article
Open AccessLipid metabolism and MAPK-ICE1 cascade play crucial roles in cold tolerance of banana
Low temperature is a major environmental factor that limits the growth, yield, and geographical distribution of Cavendish and Dajiao bananas (Musa spp.). Dajiao bananas exhibit a significantly higher cold toleran...
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Article
Open AccessThe non-linear relationship between serum albumin and diabetic retinopathy in type 2 diabetes mellitus: a secondary analysis based on a cross-sectional study
Most studies had shown a linear relationship between serum albumin (sALB) and the prevalence of diabetic retinopathy (DR). Thus, the purpose of this study is to investigate whether their relationship is non-li...
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Article
Combined experimental and simulation study on corrosion behavior of B10 copper–nickel alloy welded joint under local turbulence
The corrosion behavior of B10 copper–nickel alloy welded joints in seawater pipeline system was analyzed under local turbulence induced by weld residual height. The corrosion behavior was evaluated by array el...
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Open AccessA closer association between blood urea nitrogen and the probability of diabetic retinopathy in patients with shorter type 2 diabetes duration
Blood urea nitrogen (BUN) is an indicator of renal function and catabolic status in human body. Diabetic retinopathy (DR) is a major microvascular complication of diabetes mellitus (DM) and a serious threat to...
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Article
Effect of Intensive Oropharyngeal Training on Radiotherapy-Related Dysphagia in Nasopharyngeal Carcinoma Patients
To evaluate the effect of intensive oropharyngeal functional training on swallowing in patients with dysphagia after radiotherapy for nasopharyngeal carcinoma.
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Article
Open AccessCholesterol affects the relationship between albumin and major adverse cardiac events in patients with coronary artery disease: a secondary analysis
We aimed to examine whether the efficacy of the risk of poor prognosis in patients with coronary artery disease is jointly affected by total cholesterol and baseline serum albumin in a secondary analysis of pr...
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Open AccessDetection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...
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Article
Study on the Triaxial Unloading Creep Mechanical Properties and Damage Constitutive Model of Red Sandstone Containing a Single Ice-Filled Flaw
The freezing method is an effective approach for constructing coal mine shafts through water-rich soft rock strata. The frozen wall produced by this technique stops the movement of water and offers temporary s...
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Article
Tailoring MXene-Based Materials for Sodium-Ion Storage: Synthesis, Mechanisms, and Applications
Advanced electrodes with excellent rate performance and cycling stability are in demand for the fast development of sodium storage. Two-dimensional (2D) materials have emerged as one of the most investigated s...
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Article
Open AccessPrevalence and genetic diversity of Echinorhynchus gymnocyprii (Acanthocephala: Echinorhynchidae) in schizothoracine fishes (Cyprinidae: Schizothoracinae) in Qinghai-Tibetan Plateau, China
The schizothoracine fishes, an excellent model for several studies, is a dominant fish group of the Qinghai-Tibet Plateau (QTP). However, species populations have rapidly declined due to various factors, and i...
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Article
Open AccessTotal saponins of Bolbostemma paniculatum (maxim.) Franquet exert antitumor activity against MDA-MB-231 human breast cancer cells via inhibiting PI3K/Akt/mTOR pathway
The aim of the present study was to examine the effects of the Bolbostemma paniculatum (Maxim.) Franquet (BP) active compound, BP total saponins (BPTS), on MDA-MB-231 cells, and investigate the underlying mechani...
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Article
Open AccessOutcomes of the national programme on prevention of mother-to-child transmission of hepatitis B virus in China, 2016–2017
In addition to providing free hepatitis B vaccine (HBvacc) series to all infants in China since 2005, the national programme on prevention of mother-to-child transmission (PMTCT) of hepatitis B virus (HBV) sta...
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Article
Open AccessNotch3 inhibits epithelial–mesenchymal transition in breast cancer via a novel mechanism, upregulation of GATA-3 expression
Notch3 and GATA binding protein 3 (GATA-3) have been, individually, shown to maintain luminal phenotype and inhibit epithelial–mesenchymal transition (EMT) in breast cancers. In the present study, we report th...
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Open AccessMultimorbidity Analysis According to Sex and Age towards Cardiovascular Diseases of Adults in Northeast China
Non-communicable diseases (NCDs) are great challenges in public health, where cardiovascular diseases (CVD) accounted for the large part of mortality that caused by NCDs. Multimorbidity is very common in NCDs ...
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Open AccessAssociation of Blood Pressure with Fasting Blood Glucose Levels in Northeast China: A Cross-Sectional Study
Hypertension and diabetes mellitus (DM) have become major public health issues, and previous studies have shown that there is an association between hypertension and DM. However, there is a lack of detailed in...
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Article
Open AccessA Study on the Factors Influencing Triglyceride Levels among Adults in Northeast China
Triglyceride (TG) abnormalities are the most prevalent type of dyslipidaemia in the people of northeast China. Many researchers have investigated the prevalence, treatment and control of TG abnormalities, but ...
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Article
Microseismic Precursory Characteristics of Rock Burst Hazard in Mining Areas Near a Large Residual Coal Pillar: A Case Study from Xuzhuang Coal Mine, Xuzhou, China
Identification of precursory characteristics is a key issue for rock burst prevention. The aim of this research is to provide a reference for assessing rock burst risk and determining potential rock burst risk...
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Article
Synthesis of and ion recognition by the novel Schiff base macrocyclic compounds containing triazine
Several novel Schiff base macrocyclic compounds containing triazine were synthesized from cyanuric chloride, diethylamine, p-nitrophenol, p-phthalaldehyde, m-phthalaldehyde, and o-phthalaldehyde. Triazine macrocy...