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Article
Open AccessDeep eutectic solvent self-assembled reverse nanomicelles for transdermal delivery of sparingly soluble drugs
Transdermal delivery of sparingly soluble drugs is challenging due to their low solubility and poor permeability. Deep eutectic solvent (DES)/or ionic liquid (IL)-mediated nanocarriers are attracting increasin...
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Article
Open AccessIntraoperative quantitative crystalline lens nuclear opacities analysis based on crystalline lenSx platform
The main objective is to quantify the lens nuclear opacity using spectral-domain optical coherence tomography (SD-OCT) and to evaluate its association with Lens Opacities Classification System III (LOCS-III) s...
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Article
Open AccessBrahma-related gene 1 acts as a profibrotic mediator and targeting it by micheliolide ameliorates peritoneal fibrosis
Progressive peritoneal fibrosis is a worldwide public health concern impacting patients undergoing peritoneal dialysis (PD), yet there is no effective treatment. Our previous study revealed that a novel compou...
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Article
Different strengthening effects of amino and nitro groups on the bisphenol A adsorption of an aluminum metal-organic framework in aqueous solution
In recent years, metal-organic frameworks (MOFs) have been employed in numerous applications for adsorption. Researchers synthesize new MOFs by various methods, including the introduction of functional groups....
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Article
Open AccessA PD-L1-targeting chimeric switch receptor enhances efficacy of CAR-T cell for pleural and peritoneal metastasis
Pleural and peritoneal metastasis accompanied by malignant pleural effusion (MPE) or malignant ascites (MA) is frequent in patients with advanced solid tumors that originate from the lung, breast, gastrointest...
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Article
AKR1C3 regulated by NRF2/MAFG complex promotes proliferation via stabilizing PARP1 in hepatocellular carcinoma
Aldo-keto reductase family 1 member C3 (AKR1C3) serves as a contributor to numerous kinds of tumors, and its expression is elevated in patients with hepatocellular carcinoma (HCC). However, the biological func...
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Article
Open AccessLocalization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells
TFPI-2 has recently been recognized as a tumor suppressor, which not only plays a fundamental role in modulation of ECM integrity, but also involves the regulation of many oncogenes. In this study, we investig...
