-
Article
Open AccessA distinction between Fritillaria Cirrhosa Bulbus and Fritillaria Pallidiflora Bulbus via LC–MS/MS in conjunction with principal component analysis and hierarchical cluster analysis
Fritillaria Cirrhosa Bulbus (known as chuanbeimu in Chinese, FCB) is one of the most used Chinese medicines for lung disease. However, a variety of substitutes have entered the market, with Fritillaria Pallidiflo...
-
Article
Open AccessLearn from antibody–drug conjugates: consideration in the future construction of peptide-drug conjugates for cancer therapy
Cancer is one of the leading causes of death worldwide due to high heterogeneity. Although chemotherapy remains the mainstay of cancer therapy, non-selective toxicity and drug resistance of mono-chemotherapy i...
-
Article
Open AccessDTX-P7, a peptide–drug conjugate, is highly effective for non-small cell lung cancer
Despite tremendous success of molecular targeted therapy together with immunotherapy, only a small subset of patients can benefit from them. Chemotherapy remains the mainstay treatment for most of tumors inclu...
-
Article
Continuous Production of Dimethyl Ether from Methane and Carbon Dioxide
The dry reforming of CH4 (with CO2) at 800 °C under 1 MPa to synthesis gas and the synthesis of dimethyl ether (DME) from synthesis gas were combined. A Ni/(MgO)3·Al2O3 catalyst derived from Mg3Ni3Al2(OH)16CO3·xH
-
Article
Heterogeneous carbonylation of dimethyl ether to methyl acetate over bifunctional catalysts containing Rh and heteropoly acids
The carbonylation of dimethyl ether to methyl acetate was carried out in a high-pressure flowed fix-bed reaction system over heterogeneous halide-free catalysts. The TG curves indicated that solid 12-tungstosi...
-
Article
Effects of Li and Al2O3 support on the improvement of light hydrocarbons selectivity in Ru-based Fischer–Tropsch reaction
The catalytic activities directing for an improvement of light olefin (C2′–C4′) selectivity were investigated on the RuMnLi/Al2O3 Fischer–Tropsch synthesis catalysts in a low pressure fixed-bed reactor. The C2′–C...
-
Article
Antagomir-1290 suppresses CD133+ cells in non-small cell lung cancer by targeting fyn-related Src family tyrosine kinase
Cancer stem-like cells (CSLCs) are involved in cancer initiation, development, and metastasis, and microRNAs (miRNAs) play pivotal roles in regulating CSLCs. miRNA-based therapeutic strategy associated with CS...
-
Article
Synthesis of mixed alcohols from synthesis gas over alkali and Fischer–Tropsch metals modified MoS2/Al2O3-montmorillonite catalysts
A series of modified MoS2-supported catalysts was investigated for the synthesis of mixed alcohols from synthesis gas in a high-pressure gas–solid flow reaction system. Al2O3-pillared montmorillonite (denoted as ...
-
Article
Selective hydrocarbon production by the hydrocracking of glucose
Re-modified Pt/SiO2–Al2O3 catalysts, which were active for the direct hydrotreating of jatropha oil into C18 hydrocarbons, were found to be effective for glucose transformation into C6 alkanes. At 350 °C and gluc...
-
Article
Aggravation Effect of Isoflurane on Aβ25–35-Induced Apoptosis and Tau Hyperphosphorylation in PC12 Cells
Some anesthetics have been suggested to induce Alzheimer’s disease (AD) neuro-pathogenesis. Increasing evidence indicates that hyperphosphorylated tau plays a key role in the pathogenic events that occur in AD...
-
Article
Effect of secondary additives (Li, Mn) in Fe-promoted Rh/TiO2 catalysts for the synthesis of ethanol from syngas
Li and Mn have been used as secondary additives in Rh–Fe/TiO2 (Rh catalyst, TiO2 support, and Fe promoter) for the synthesis of ethanol from syngas. Introducing Li or Mn in Rh–Fe/TiO2 slightly decreased the catal...
-
Article
Hydrocracking of Biomass-Derived Materials into Alkanes in the Presence of Platinum-Based Catalyst and Hydrogen
Renewable green C2–C9 alkanes can be directly produced by Pt/H-ZSM-5-catalyzed hydrocracking of biomass-derived materials, no pre-treated or pre-treated by alcohol. The pre-treatment of cellulose in 1-hexanol ...
-
Article
cDNA Microarray Analysis of Gene Expression in the Cerebral Cortex and Hippocampus of BALB/c Mice Subjected to Chronic Mild Stress
Depressive disorders are devastating metal illness that can lead to deterioration in the social and occupational functioning of affected individuals. The etiology and pathophysiology of depression remain unkno...
-
Article
Selective Hydrocracking of Fischer–Tropsch Waxes to High-quality Diesel Fuel Over Pt-promoted Polyoxocation-pillared Montmorillonites
Polyoxocation ([AlO4Al12(OH)24(H2O)12]7+ and [Zr4(OH)14(H2O)10]2+)-pillared montmorillonites were prepared by ion exchange, and they were used as solid acid catalysts, in comparison to some other solid acids, for...
-
Article
Zr- and Li-Modified Ru/Sio2 Catalysts for Fischer–Tropsch Synthesis
We have found that Zr- and Li-modified Ru/SiO2 catalysts (Q-15) are extremely stable and can be used in FT synthesis to maintain the conversion rate of CO constant even after 33 h. Modification of Ru/SiO2 by Zr (...
-
Article
Melatonin Regulates the Viability and Differentiation of Rat Midbrain Neural Stem Cells
(1) Neurogenesis driven by neural stem cells (NSCs) is regulated by physiological and pathological factors. Melatonin (MT) has profound neurotrophic and neuroprotective effects. Hence, we studied the role of M...
-
Article
Synthesis of Zr-containing FSM-16 as an effective support for Co catalyst in the Fischer-Tropsch synthesis
Zr4+ ions have been introduced into the framework of FSM-16 using a sol-gel method at Si/Zr ≥ 200 (molar ratio). Co/Zr-FSM-16 showed high CO conversion and a high selectivity for C5+ hydrocarbons in the Fischer-T...
-
Article
In vitro inhibitory effect of polyoxometalates on human tumor cells
H7[NiV13O38] was synthesized from K7[NiV13O38] using an ion exchange method. Then Pr2H[NiV13O38] was obtained by double decomposition of H7[NiV13O38] with Pr2(CO3)3. The actual amount of praseodymium measured by ...
-
Article
Oxidation of Propylene to Propylene Oxide with Molecular Oxygen by Pd(OAc)2/Ti—Al-HMS/CH3OH Catalyst System
The Pd(OAc)2/Ti—Al-HMS/CH3OH catalyst system showed 61.2% selectivity for PO at 42.8% propylene conversion for the oxidation of propylene with molecular oxygen in an autoclave reactor at 373 K for 4 h. The cataly...
-
Article
Selective Oxidation of Propylene to Propylene Oxide by Molecular Oxygen over Ti-Al-HMS Catalysts
Ti- and Al-containing hexagonal mesoporous silicas (HMS) were synthesized at ambient temperature using dodecylamine as surfactant, and the resultant compounds were used as catalysts for the oxidation of propyl...
