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Article
Open AccessDDAH-1 maintains endoplasmic reticulum-mitochondria contacts and protects dopaminergic neurons in Parkinson’s disease
The loss of dopaminergic neurons in the substantia nigra is a hallmark of pathology in Parkinson’s disease (PD). Dimethylarginine dimethylaminohydrolase-1 (DDAH-1) is the critical enzyme responsible for the de...
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Article
Open AccessComparative analysis of mitochondrial genomes of maize CMS-S subtypes provides new insights into male sterility stability
Cytoplasmic male sterility (CMS) is a trait of economic importance in the production of hybrid seeds. In CMS-S maize, exerted anthers appear frequently in florets of field-grown female populations where only c...
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Article
A newly characterized allele of ZmR1 increases anthocyanin content in whole maize plant and the regulation mechanism of different ZmR1 alleles
The novel ZmR1CQ01 allele for maize anthocyanin synthesis was identified, and the biological function and regulatory molecular mechanisms of three ZmR1 alleles were unveiled.
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Article
Spatiotemporal heterogeneities and driving factors of water quality and trophic state of a typical urban shallow lake (Taihu, China)
Water quality deterioration and eutrophication of urban shallow lakes are global ecological problems with increasing concern and greater environmental efforts. In this study, spatiotemporal changes of water qu...
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Article
A New Convolutional Neural Network Architecture for Automatic Segmentation of Overlap** Human Chromosomes
In clinical diagnosis, karyoty** is carried out to detect genetic disorders due to chromosomal aberrations. Accurate segmentation is crucial in this process that is mostly operated by experts. However, it is...
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Article
Open AccessNeurotransmitter-stimulated neuron-derived sEVs have opposite effects on amyloid β-induced neuronal damage
The ratio of excitatory to inhibitory neurotransmitters is essential for maintaining the firing patterns of neural networks, and is strictly regulated within individual neurons and brain regions. Excitatory to...
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Article
Open AccessStalk architecture, cell wall composition, and QTL underlying high stalk flexibility for improved lodging resistance in maize
Stalk fracture caused by strong wind can severely reduce yields in maize. Stalks with higher stiffness and flexibility will exhibit stronger lodging resistance. However, stalk flexibility is rarely studied in ...
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Article
Open AccessSequence polymorphism of the waxy gene in waxy maize accessions and characterization of a new waxy allele
Waxy maize has many excellent characteristics in terms of its nutritional and economic value. In recent decades, the waxy maize germplasm has increased dramatically as a result of different selection methods. ...
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Article
Two-dimensional elasticity solution for free vibration of simple-supported beams with arbitrarily and continuously varying thickness
This paper studies the analytical solution for the vibration of simply supported beams with arbitrarily and continuously varying thickness based on the two-dimensional elasticity theory. The general expression...
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Article
Open AccessCUBIC: an atlas of genetic architecture promises directed maize improvement
Identifying genotype-phenotype links and causative genes from quantitative trait loci (QTL) is challenging for complex agronomically important traits. To accelerate maize gene discovery and breeding, we presen...
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Article
Open AccessGenome-wide identification, phylogeny and expression analysis of the PME and PMEI gene families in maize
Pectins, the major components of cell walls in plants, are synthesized and secreted to cell walls as highly methyl-esterified polymers and then demethyl-esterified by pectin methylesterases (PMEs). The PMEs ar...
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Article
Open AccessMulti-omics analysis of the development and fracture resistance for maize internode
The maize stalk is an important mechanical supporting tissue. The stalk fracture resistance is closely related to lodging resistance, and thus the yield. In this study, we showed that the basal zone (BZ) was m...
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Article
Resveratrol Abrogates Hypoxia-Induced Up-Regulation of Exosomal Amyloid-β Partially by Inhibiting CD147
Hypoxia promotes both total extracellular and exosomal amyloid-β (Aβ) production and aggravates Alzheimer’s disease (AD). Resveratrol (RSV) has been proved to be neuroprotective in AD models, and down-regulate...
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Article
Map** of quantitative trait loci for seedling salt tolerance in maize
Improved salt tolerance is a major goal for maize breeders, but the control of salt tolerance-related traits in maize is poorly understood. A set of 209 doubled haploid (DH) lines derived from the maize hybrid...
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Article
Open AccessDynamic plant height QTL revealed in maize through remote sensing phenoty** using a high-throughput unmanned aerial vehicle (UAV)
Plant height (PH) is a key factor in maize (Zea mays L.) yield, biomass, and plant architecture. We investigated the PH of diverse maize inbred lines (117 temperate lines, 135 tropical lines) at four growth stage...
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Article
The lateralized arcuate fasciculus in developmental pitch disorders among mandarin amusics: left for speech and right for music
The arcuate fasciculus (AF) is a neural fiber tract that is critical to speech and music development. Although the predominant role of the left AF in speech development is relatively clear, how the AF engages ...
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Article
Open AccessPredictors of early-onset post-ischemic stroke depression: a cross-sectional study
Post-stroke depression (PSD) seriously affects the rehabilitation of nerve function and quality of life. However, the pathogenesis of PSD is still not clear. This study aimed to investigate the demographic, cl...
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Article
Open AccessMap** of a major QTL for salt tolerance of mature field-grown maize plants based on SNP markers
Salt stress significantly restricts plant growth and production. Maize is an important food and economic crop but is also a salt sensitive crop. Identification of the genetic architecture controlling salt tole...
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Article
Molecular map** of quantitative trait loci for three kernel-related traits in maize using a double haploid population
Kernel size and kernel weight are important factors possibly involved in the determination of grain yield in maize, so identifying the genetic basis of kernel-related traits provides insights into the breeding...
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Article
Open AccessFunctional divergence and origin of the DAG-like gene family in plants
The nuclear-encoded DAG-like (DAL) gene family plays critical roles in organelle C-to-U RNA editing in Arabidopsis thaliana. However, the origin, diversification and functional divergence of DAL genes remain uncl...
