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Kidney volume—a crystal ball for ADPKD prognosis?

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  1. Article

    Open Access

    Evaluation of the efficacy of HEMO2life®, a marine OXYgen carrier for Organ Preservation (OxyOp2) in renal transplantation: study protocol for a multicenter randomized trial

    Preventing ischemia‒reperfusion injury (IRI) is a major issue in kidney transplantation, particularly for transplant recipients receiving a kidney from extended criteria donors (ECD). The main consequence of I...

    Yannick Le Meur, Emmanuel Nowak, Benoit Barrou, Antoine Thierry, Lionel Badet… in Trials (2023)

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  2. Article

    Open Access

    Pharmacokinetics of Prolonged-Release Once-Daily Formulations of Tacrolimus in De Novo Kidney Transplant Recipients: A Randomized, Parallel-Group, Open-Label, Multicenter Study

    Different prolonged-release formulations of tacrolimus are available. To date, the pharmacokinetic (PK) profile of LCP-tacrolimus (LCPT; Envarsus®) has not been compared with PR-Tac (Advagraf®) in de novo kidney ...

    Nassim Kamar, Elisabeth Cassuto, Giovanni Piotti, Mirco Govoni… in Advances in Therapy (2019)

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  3. Article

    Open Access

    EPURE Transplant (Eplerenone in Patients Undergoing Renal Transplant) study: study protocol for a randomized controlled trial

    Despite advances in immunosuppressive therapy, kidney graft survival has failed to improve during the last decades. Ischemia/reperfusion injury (IRI) is one of the main pathophysiological mechanisms underlying...

    Sophie Girerd, Luc Frimat, Didier Ducloux, Yannick Le Meur, Christophe Mariat… in Trials (2018)

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  4. Article

    Open Access

    Novel long-range regulatory mechanisms controlling PKD2 gene expression

    Cis-regulatory elements control gene expression over large distances through the formation of chromatin loops, which allow contact between enhancers and gene promoters. Alterations in cis-acting regulatory system...

    Stéphanie Moisan, Stéphanie Levon, Emilie Cornec-Le Gall, Yannick Le Meur… in BMC Genomics (2018)

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