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    Article

    Cryo-EM structure and protease activity of the type III-E CRISPR-Cas effector

    The recently discovered type III-E CRISPR-Cas effector Cas7-11 shows promise when used as an RNA manipulation tool, but its structure and the mechanisms underlying its function remain unclear. Here we present ...

    Yangao Huo, Hongshen Zhao, Qinghua Dong, Tao Jiang in Nature Microbiology (2023)

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    Article

    A male germ-cell-specific ribosome controls male fertility

    Ribosomes are highly sophisticated translation machines that have been demonstrated to be heterogeneous in the regulation of protein synthesis1,2. Male germ cell development involves complex translational regulat...

    Huiling Li, Yangao Huo, ** He, Li** Yao, Hao Zhang, Yiqiang Cui, Huijuan **ao in Nature (2022)

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    Article

    Cryo-EM structure of Type III-A CRISPR effector complex

    Yangao Huo, Tao Li, Nan Wang, Qinghua Dong, **angxi Wang, Tao Jiang in Cell Research (2018)