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Open AccessCanagliflozin alleviates pulmonary hypertension by activating PPARγ and inhibiting its S225 phosphorylation
Pulmonary hypertension (PH) is a progressive fatal disease with no cure. Canagliflozin (CANA), a novel medication for diabetes, has been found to have remarkable cardiovascular benefits. However, few studies h...
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Open AccessInvestigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse
Aging is a physiological condition accomplished with persistent low-grade inflammation and metabolic disorders. FGF21 has been reported to act as a potent longevity determinant, involving inflammatory response...