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Article
Open AccessExploring caspase functions in mouse models
Caspases are enzymes with protease activity. Despite being known for more than three decades, caspase investigation still yields surprising and fascinating information. Initially associated with cell death and...
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Article
A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet (Setaria italica)
Bin Han and colleagues report de novo assembly of the genome of a wild progenitor (Setaria viridis) of foxtail millet and low-pass resequencing of 916 diverse foxtail millet varieties. They identify 0.8 million c...
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Article
Heterozygous loss of Six5 in mice is sufficient to cause ocular cataracts
Myotonic dystrophy (DM) is an autosomal dominant disorder characterized by skeletal muscle wasting, myotonia, cardiac arrhythmia, hyperinsulinaemia, mental retardation and ocular cataracts1. The genetic defect in...