13 Result(s)
within
Yanfeng Yao
Virology
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Article
Open AccessBoth chimpanzee adenovirus-vectored and DNA vaccines induced long-term immunity against Nipah virus infection
Nipah virus (NiV) is a highly lethal zoonotic paramyxovirus that poses a severe threat to humans due to its high morbidity and the lack of viable countermeasures. Vaccines are the most crucial defense against ...
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Open AccessCorrection to: Transmission of H7N9 influenza virus in mice by different infective routes
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Open AccessCorrection to: The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus
An amendment to this paper has been published and can be accessed via the original article.
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Avian Influenza A (H7N9) Virus in a Wild Land Bird in Central China, Late 2015
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Characterization of a reassortant H11N9 subtype avian influenza virus isolated from bean goose along the East Asian–Australian flyway
During the surveillance of avian influenza viruses in the Dongxi Lake wetland of Hubei in 2015–2016, an H11N9 avian influenza virus was isolated from a bean goose (Anser fabalis). Phylogenetic analysis showed tha...
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MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2
Middle East respiratory syndrome coronavirus (MERS-CoV) causes sporadic zoonotic disease and healthcare-associated outbreaks in human. MERS is often complicated by acute respiratory distress syndrome (ARDS) an...
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Distribution of enterovirus 71 RNA in inflammatory cells infiltrating different tissues in fatal cases of hand, foot, and mouth disease
In previous studies of hand, foot, and mouth disease patients fatally infected with enterovirus 71 (EV71), the distribution of viral protein, but not the genome, was determined. To understand the pathogenesis ...
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Open AccessTransmission of H7N9 influenza virus in mice by different infective routes
On 19 February 2013, the first patient infected with a novel influenza A H7N9 virus from an avian source showed symptoms of sickness. More than 349 laboratory-confirmed cases and 109 deaths have been reported ...
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Comparative analysis of antibody induction and protection against influenza virus infection by DNA immunization with HA, HAe, and HA1 in mice
Plasmid DNA vaccines are considered alternatives to inactivated influenza virus vaccines to control influenza. Vaccination with a hemagglutinin (HA)-, HA ectodomain (HAe)-, or HA subunit 1 (HA1)-based vaccine...
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Evaluation of neutralizing efficacy of monoclonal antibodies specific for 2009 pandemic H1N1 influenza A virus in vitro and in vivo
Pandemic influenza A virus (H1N1) 2009 poses a serious public-health challenge worldwide. To characterize the neutralizing epitopes of this virus, we generated a panel of eight monoclonal antibodies (mAbs) aga...
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Open AccessThe mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus
The current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.
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Immunization with cytomegalovirus envelope glycoprotein M and glycoprotein N DNA vaccines can provide mice with complete protection against a lethal murine cytomegalovirus challenge
Human cytomegalovirus virions contain three major glycoprotein complexes (gC I, II, III), all of which are required for CMV infectivity. These complexes also represent major antigenic targets for anti-viral im...
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Characterization of low-pathogenic H6N6 avian influenza viruses in central China
Three strains of H6N6 subtype avian influenza virus (AIV) were isolated from live-poultry markets of central China during 2009-2010. A phylogenetic analysis showed that these isolates originated from gene reas...
