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Article
Optimized-dose lidocaine-loaded sulfobutyl ether β-cyclodextrin/hyaluronic acid hydrogels to improve physical, chemical, and pharmacological evaluation for local anesthetics and drug delivery systems
Local anesthetics (LAs) are a class of drugs, which have wide applications in the treatment of post-operative pain care management. Long-acting LAs that can be given as a single dose analgesic are desperately ...
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Article
Theoretical insight into the BH3·HCN adsorption on the Co(100) and Co(110) surfaces as hydrogen storage
Fifteen configurations and adsorption energies of the adsorption sites of BH3∙∙∙HCN on Co(100) and Co(110) surfaces were investigated using the density functional theory. The results show that after BH3∙∙∙HCN is ...
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Article
Concurrent supercritical fluid chromatographic analysis of terpene lactones and ginkgolic acids in Ginkgo biloba extracts and dietary supplements
Supercritical fluid chromatography was used to resolve and determine ginkgolic acids (GAs) and terpene lactones concurrently in ginkgo plant materials and commercial dietary supplements. Analysis of GAs (C13:0...
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Article
Quantification and characterization of alkaloids from roots of Rauwolfia serpentina using ultra-high performance liquid chromatography-photo diode array-mass spectrometry
A new UHPLC-UV method has been developed for the simultaneous analysis of seven alkaloids [ajmaline (1), yohimbine (2), corynanthine (3), ajmalicine (4), serpentine (5), serpentinine (6), and reserpine (7)] from ...
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Article
Identification of Ginkgo biloba supplements adulteration using high performance thin layer chromatography and ultra high performance liquid chromatography-diode array detector-quadrupole time of flight-mass spectrometry
Ginkgo biloba is one of the most widely sold herbal supplements and medicines in the world. Its popularity stems from having a positive effect on memory and the circulatory system in clin...
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Article
A theoretical study on the strength of the C–NO2 bond and ring strain upon the formation of the intermolecular H-bonding interaction between HF and nitro group in nitrocyclopropane, nitrocyclobutane, nitrocyclopentane or nitrocyclohexane
As a follow-up to our investigation into the influence of H-bond on the C–NO2 trigger bond, a comparison of the effect of the H-bond on the ring strain energy with the C–NO2 bond dissociation energy was carried o...
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Article
A theoretical investigation into the cooperativity effect between the H∙∙∙O and H∙∙∙F– interactions and electrostatic potential upon 1:2 (F–:N-(Hydroxymethyl)acetamide) ternary-system formation
The cooperativity effects between the O/N–H∙∙∙F– anionic hydrogen-bonding and O/N–H∙∙∙O hydrogen-bonding interactions and electrostatic potentials in the 1:2 (F–:N-(Hydroxymethyl)acetamide (signed as “ha”)) terna...