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Open AccessPan-cancer multi-omics analysis of PTBP1 reveals it as an inflammatory, progressive and prognostic marker in glioma
PTBP1 is an oncogene that regulates the splicing of precursor mRNA. However, the relationship between PTBP1 expression and gene methylation, cancer prognosis, and tumor microenvironment remains unclear. The ex...
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Article
Positron Emission Tomography Imaging of Synaptic Dysfunction in Parkinson’s Disease
Parkinson’s disease (PD) is one of the most common neurodegenerative diseases with a complex pathogenesis. Aggregations formed by abnormal deposition of alpha-synuclein (αSyn) lead to synapse dysfunction of th...
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Article
Influence of iron phosphate on the performance of lithium iron phosphate as cathodic materials in rechargeable lithium batteries
Iron phosphate (FePO4·2H2O) has emerged as the mainstream process for the synthesis of lithium iron phosphate (LiFePO4), whereas FePO4·2H2O produced by different processes also has a great influence on the perfor...
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Article
PGE2 Overexpressing Human Embryonic Stem Cell Derived Mesenchymal Stromal Cell Relieves Liver Fibrosis in an Immuno-suppressive Manner
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Article
XGB-Northern Goshawk Optimization: Predicting the Compressive Strength of Self-Compacting Concrete
The contributions of this study, which include enhanced predictive precision and the integration of supplementary admixtures, may be effectively used in real-world scenarios to optimize self-compacting concrete (
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Article
Open AccessExtracorporeal photopheresis reduces inflammation and joint damage in a rheumatoid arthritis murine model
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammatory reactions and tissue damage in the joints. Long-term drug use in clinical practice is often accompanied by adverse reactions. Ex...
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Article
The role of PI3K/Akt signaling pathway in chronic kidney disease
Chronic kidney disease (CKD), including chronic glomerulonephritis, IgA nephropathy and diabetic nephropathy, are common chronic diseases characterized by structural damage and functional decline of the kidney...
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Article
Nuclear psychiatric imaging: the trend of precise diagnosis for mental disorders
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Article
Correlation of Gut Microbiota with Children Obesity and Weight Loss
Children obesity is a serious public health problem drawing much attention around the world. Recent research indicated that gut microbiota plays a vital role in children obesity, and disturbed gut microbiota i...
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Research progress on reproductive system damage caused by high altitude hypoxia
The high altitude area is characterized by low pressure and hypoxia, and rapidly entering the high altitude area will cause a series of damage to the body. Some studies have shown that hypoxia can cause damage...
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Open AccessFilgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis
To assess cigarette smoking’s effects on efficacy of the preferential Janus kinase (JAK) 1 inhibitor filgotinib and drug persistence in patients with rheumatoid arthritis (RA).
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Medical image Generative Pre-Trained Transformer (MI-GPT): future direction for precision medicine
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International consensus on clinical use of presynaptic dopaminergic positron emission tomography imaging in parkinsonism
Presynaptic dopaminergic positron emission tomography (PET) imaging serves as an essential tool in diagnosing and differentiating patients with suspected parkinsonism, including idiopathic Parkinson’s disease ...
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Article
In vivo cerebral metabolic and dopaminergic characteristics in multiple system atrophy with orthostatic hypotension
Multiple system atrophy (MSA) is a rare neurodegenerative disease, often presented with orthostatic hypotension (OH), which is a disabling symptom but has not been very explored. Here, we investigated MSA pati...
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Aging imaging: the future demand of health management
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Trichoscopy for early diagnosis and follow-up of pet-related neonatal tinea capitis
We report infant zigzag hairs as a distinct trichoscopic sign for follow up a case of pet-related newborn tinea capitis due to Microsporum canis. Formation of infant zigzag hairs due to ectothrix M. canis infecti...
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Open AccessCorrection to: [18F]FDG PET/MRI combined with chest HRCT in early cancer detection: a retrospective study of 3020 asymptomatic subjects
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Open Access[18F]FDG PET/MRI combined with chest HRCT in early cancer detection: a retrospective study of 3020 asymptomatic subjects
PET/MRI has become an important medical imaging approach in clinical practice. In this study, we retrospectively investigated the detectability of fluorine-18 (18F)-fluorodeoxyglucose positron emission tomography...
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Open AccessInternational Nuclear Medicine Consensus on the Clinical Use of Amyloid Positron Emission Tomography in Alzheimer’s Disease
Alzheimer’s disease (AD) is the main cause of dementia, with its diagnosis and management remaining challenging. Amyloid positron emission tomography (PET) has become increasingly important in medical practice...
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Article
Open AccessComparison and fusion prediction model for lung adenocarcinoma with micropapillary and solid pattern using clinicoradiographic, radiomics and deep learning features
To investigate whether the combination scheme of deep learning score (DL-score) and radiomics can improve preoperative diagnosis in the presence of micropapillary/solid (MPP/SOL) patterns in lung adenocarcinom...
