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Article
The potential Role of CYP2D6*10(c.100 C>T) Gene Polymorphism in Kidney Injury of Patients with Hypertension Complicated with Non-Elevated Cystatin C
This study aims to investigate the potential role of CYP2D6*10 (c.100 C>T) gene polymorphism in renal function injury among hypertensive patients without elevated cystatin C. A cohort of hypertensive patients ...
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Article
Acoustic emission characteristics and fracture mechanism of cemented tailings backfill under uniaxial compression: experimental and numerical study
Cemented tailings backfill (CTB) is the most cost-effective and environmentally friendly method to recycle tailings for filling mining. It is of great significance to study the fracture mechanism of CTB for sa...
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Article
Experimental study on the brush tool–assisted shear-thickening polishing of cemented carbide insert
To obtain uniform surface roughness of the complex cutting edge of the cemented carbide insert in the polishing process, a novel method, brush tool–assisted shear-thickening polishing (B-STP), was proposed in ...
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Article
Open AccessMediators of SARS-CoV-2 entry are preferentially enriched in cardiomyocytes
The coronavirus disease 2019 (COVID-19) has spread rapidly around the world. In addition to common respiratory symptoms such as cough and fever, some patients also have cardiac injury, however, the mechanism o...
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Chapter and Conference Paper
PD-DARTS: Progressive Discretization Differentiable Architecture Search
Architecture design is a crucial step for neural-network-based methods, and it requires years of experience and extensive work. Encouragingly, with recently proposed neural architecture search (NAS), the archi...
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Chapter and Conference Paper
Towards Accurate Panel Detection in Manga: A Combined Effort of CNN and Heuristics
Panels are the fundamental elements of manga pages, and hence their detection serves as the basis of high-level manga content understanding. Existing panel detection methods could be categorized into heuristic...
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Article
Open AccessDapagliflozin improves left ventricular remodeling and aorta sympathetic tone in a pig model of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) is a difficult disease with high morbidity and mortality rates and lacks an effective treatment. Here, we report the therapeutic effect of dapagliflozin, ...
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Article
Open AccessBET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemia
Targeted therapy has always been the focus in develo** therapeutic approaches in cancer, especially in the treatment of acute myeloid leukemia (AML). A new small molecular inhibitor, JQ1, targeting BRD4, whi...
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Article
Hyaluronic acid binding protein 1 overexpression is an indicator for disease-free survival in cervical cancer
Hyaluronic acid binding protein 1 (HABP1) is reported to overexpress in various cancer tissues and may therefore contribute to oncogenesis. However, the status of HABP1 expression in cervical cancer (CC) remai...
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Article
Comic storyboard extraction via edge segment analysis
Comic storyboard extraction aims to decompose the comic image into several storyboards (or frames), which is the key technique to produce the digital comic documents suitable for mobile reading. Previous metho...
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Article
Open AccessPrognostic value of late gadolinium enhancement cardiac magnetic resonance in hypertrophic cardiomyopathy: a meta-analysis
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Chapter and Conference Paper
Reconfiguring Multi-Rate Wi-Fi Mesh Networks with Flow Disruption Constraints
Wi-Fi mesh networks (WMNs) have been considered as a promising data-networking infrastructure in port-logistics environments. In such networks, it has been known that user traffic has a periodic characteristic...
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Article
MutS-mediated enrichment of mutated DNA produced by directed evolution in vitro
Directed evolution in vitro is a powerful tool in the study and design of protein function. However, screening the desired mutants is a difficult task. To facilitate the screening, a method is proposed to elim...
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Article
Cloning and characterization of NAD-dependent protein deacetylase (Rv1151c) from Mycobacterium tuberculosis
Sir2 family proteins are highly conserved and catalyze a well-characterized NAD-dependent protein deacetylation reaction that regulates multiple cellular processes including aging, gene silencing, cellular dif...
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Article
Glycerol-salt Mediated Stacking of Nucleic Acids in CZE
Nucleic acid samples with high concentrations of salt could be stacked and well separated during capillary zone electrophoresis (CZE) by adding glycerol into the samples and using a Tris-Borate-EDTA (TBE) buff...
