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  1. No Access

    Article

    Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis

    Sphingomyelin (SM) has key roles in modulating mammalian membrane properties and serves as an important pool for bioactive molecules. SM biosynthesis is mediated by the sphingomyelin synthase (SMS) family, com...

    Kexin Hu, Qing Zhang, Yang Chen, **tong Yang… in Nature Structural & Molecular Biology (2024)

  2. Article

    Open Access

    Qa-SNARE syntaxin 18 mediates lipid droplet fusion with SNAP23 and SEC22B

    Lipid droplets (LDs) are dynamic lipid storage organelles that can sense and respond to changes in systemic energy balance. The size and number of LDs are controlled by complex and delicate mechanisms, among w...

    Yuhui Fu, Binbin Ding, **aoxia Liu, Shangang Zhao, Fang Chen, Linsen Li… in Cell Discovery (2023)

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